Continuity mistake: When the Simpsons are on the raft going down the river in Africa they come to a fork and have a choice of going to the left, towards a sunny and nicer area or to the right where it is rainy and gloomy. As Homer tries to steer the raft to the left as he pulls his left arm out of the water and it is covered in leeches but in the next shot of him when we see the arm again the leeches are gone. No way to remove leeches that fast.
Continuity mistake: When the school bus drops off Bart and Milhouse at the Simpson house, Bart puts his backpack on frontwards and starts krumping. When he walks through The Front door, he is still wearing his backpack on his front. It then cuts to inside the house, and we still see him coming through the door, but the backpack is gone.
Continuity mistake: When the men from Festival Cruise Lines arrive at the Simpson house, they park in the left-hand lane (closest to the house) with the car facing oncoming traffic, seen both when they first pull up and, more, in the background while informing Milhouse about his parents. But in the overhead shot of the house, the car is parked the other way around, following the direction of traffic.
Continuity mistake: In the second segment, as Roger is telling them about what happened to him, as he finishes the story of Marge and Homer saving him, in his recount Marge is wearing a shirt and bikini bottoms (the shirt is covering the bikini bra). But when they saved her, she was just wearing a bikini.
Continuity mistake: While Krusty is in the hospital talking to Sophie, he pops the IV line from his arm so the tubing hangs down from the fluid bag. But when Krusty tells Sophie that he knows she's reaching out, suddenly Krusty's IV line is properly inserted in the cannula again, only to change back to the tubing hanging down. Also, the white pillow propping up Krusty's foot vanishes and reappears during these shots. (00:05:15)
Continuity mistake: When Bart opens the door for Krusty and Sophie, Bart is standing on a floor mat, but in the next exterior shot, that indoor floor mat has vanished. Other changes include the cane's handle within Krusty's grip facing the opposite way, as well as Krusty's and Sophie's positions at the outdoor purple mat. (00:06:50)