Continuity mistake: In the 'Nightmare on Evergreen Terrace' segment, in Bart's dream you see a shadow of what looks like someone with four knife-fingers. Then when we see who it is, it is Willie holding a rake. But the rake has five tines, not four, so the shadow is wrong.
Continuity mistake: Just before Marge tries to sell Skinner the tie rack, she is writing on something. She then puts her hands down by her waist, and then brings one up to turn it on and both up to pull the motor out. The point is that the pencil and the item she had in her hands have simply vanished, and we never saw her put them down either.
Continuity mistake: When Professor Frink is explaining where Homer is, in "Homer3", Ned Flanders is leaning behind the couch between Bart and Marge, and Chief Wiggum is standing up. When Homer complains, Ned is between Marge and Chief Wiggum, who is now sitting down on the couch.
Continuity mistake: When Maggie (sitting on Marge) appears on "Tyrano-Vision," Homer waves his hand in front of her. However, we can see that he isn't leaning over too far, and in the next shot it is clear that both Bart and Lisa are sitting between Homer and Marge, so there is no way he could have reached over to her in the first place.