Home Away From Homer - S16-E20
Continuity mistake: When Homer rings the doorbell of the Flanders' former house to visit the new neighbour, it moves downwards on the door frame. In the first shot it lines up with the gap between the lock and the doorknob, but in the next shot it is beside the doorknob, and in other shots in the episode the doorbell isn't even there. Also, the glass panels on both sidelights line up with the door differently between shots.
Home Away From Homer - S16-E20
Continuity mistake: As the Simpsons are in the cinema watching "Kosovo Autumn" you can see there is a seat next to Homer to the right of screen. When Homer starts complaining about the film but cannot leave because he is stuck in his seat, the shot changes and we see him from behind however the seat that was next to him has disappeared.
Home Away From Homer - S16-E20
Continuity mistake: When Coach is cutting down trees he tells Homer that he borrowed some petrol (or 'gas' in America) from his car, and the shot goes to his car. However when Homer runs indoors the car has vanished.
Home Away From Homer - S16-E20
Continuity mistake: For "Home Away From Homer": Bart looks out his bedroom window and sees the college girls doing sexual actions in the Flanders' spare bedroom. But, there is never a window in Bart's room that could possibly face the Flanders' house. [Bart's window in many episodes does face Flander's house but in other episodes like "Bart's Friend Falls in Love" and "Bart the Mother" it faces the treehouse which is the backyard of the house.]
Home Away From Homer - S16-E20
Continuity mistake: Ned's front door before he and his family leaves opens on the left side (when looking at it from outside), but after the "Coach" has moved in, it opens on the opposite side.
Home Away From Homer - S16-E20
Continuity mistake: When Homer tries to leave his seat in the cinema and complains about eating the apple, the shot shows his body fat has wedged him in the seat. However we can see from all the shots before this that the fat was never wedged in like it was when he was trying to leave.
Home Away From Homer - S16-E20
Continuity mistake: When Homer hits Coach with a chair, the white stripe that was on Coach's tracksuits has gone.
Home Away From Homer - S16-E20
Continuity mistake: When Homer meets Coach for the first time (and maybe another point in the episode), the position of Ned's house's window frames to the side of the door change between shots.
Home Away From Homer - S16-E20
Continuity mistake: We see Coach cutting down trees in Flanders' former driveway. However there had never been any trees in Flanders' driveway.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer