Continuity mistake: At the end in the hospital, Maggie's bow is red for a second, then it changes to blue.
Continuity mistake: All through out the episode, Bart draws his pictures with only one pencil, but they all end up in color when he's done.
Factual error: When the creator of Danger Dog draws a picture of Skinner on a notepad and puts it on the projector, it is perfectly visible. It shouldn't have been, seeing as the pad was so thick.
Continuity mistake: When Homer falls into the pool with green paint, most (but not all) of him is covered with paint. In the next close up shot, he's completely covered in paint.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer