Lisa's Pony - S3-E8
Continuity mistake: Homer writes '4 1/2 Reed' on his left shoe. When the owner of the music store asks him what Lisa plays, he is reading off his right shoe. (00:02:00 - 00:04:40)
Lisa's Pony - S3-E8
Continuity mistake: In the last shot of Marge and Homer's discussion of buying a pony, we can see a door on the right side of the screen. This door changes position when Lisa rides in the bedroom with her pony. (00:08:45 - 00:12:10)
Who Shot Mr. Burns? (1) - S6-E25
Continuity mistake: When Smithers and Mr Burns are eating the chocolate and see the photo, you can see that Marge's necklace changes from red to white and then back to red.
Lisa's Sax - S9-E3
Continuity mistake: In the episode 'Lisa's Sax' (season 9, ep. 3), King Toot's music store is across the street from Moe's Tavern. However, in numerous later episodes, there are stills of Moe's Tavern that show King Toot's music store next door, not across the street as in the aforementioned episode.
The Simpsons Christmas Special: Simpsons Roasting on an Open Fire - S1-E1
Continuity mistake: When Marge reveals the Christmas money from her hair, her necklace changes from red to white. (00:05:30)
Treehouse of Horror XIV - S15-E1
Continuity mistake: When the younger Professor Frink is receiving and wearing his Nobel Prize, his father goes nuts and starts stealing people's brains. The younger Frink figures out that kicking the elder Frink in the crotch will stop him. When he does, and the elder Frink falls off the stage, he is wearing the Nobel Prize, not the younger. (00:15:00)
Cape Feare - S5-E2
Continuity mistake: At the beginning of the episode when we see MacBain on TV he goes through a curtain, the curtain stays open for a second even though he isn't touching it.
My Mother the Carjacker - S15-E2
Continuity mistake: At the end of the episode when Homer is looking for another message from his mom to find out if she's really alive, Marge and the kids enter the kitchen, Marge says that it's 2 in the morning. But the clock on the wall shows that it's 9 pm.
Three Men and a Comic Book - S2-E21
Continuity mistake: When there is a rotating shot of Bart, Martin and Milhouse up in the treehouse, the shot never goes past the table, even though it should.
Brother From Another Series - S8-E16
Continuity mistake: In the scene where Sideshow Bob and his brother Cecil are arrested and sits in the the back of the police car, Cecil is missing when Sideshow Bob is talking to the people outside the car though his window. They both entered the car and they can both be seen when the car leaves.
The Secret War of Lisa Simpson - S8-E25
Continuity mistake: When Lisa has just been saved from falling, from the Eliminator at night, three boys approach. The two boys on the right swap positions between shots.
Continuity mistake: The hole in the wall made by the acid changes shape and size in several scenes.
Lisa on Ice - S6-E8
Continuity mistake: The turtle that Homer hands to Bart disappears as soon as it goes into Barts' hand, and it is never seen again.
Continuity mistake: When Millhouse spits the paper at Kearney in the cafeteria, Jimbo is seen wearing a black shirt and Dolph is wearing a green shirt yet, when Millhouse is dragged out the cafeteria by Bart, they are both wearing blue shirts. (00:16:10)
Continuity mistake: In the shower scene, we see that in front of Carl, there is a man with brown hair and a moustache in front of him, but then when the shot changes, the man has moved cubicles and a man with white hair has taken his place, and he wasn't even in the previous shot. (00:14:50)
Continuity mistake: When Chief Wiggum says, "Give him your badge," he doesn't have anything on the right side (his right) of his shirt. After the camera flashes to Bart and back, Wiggum suddenly has a badge there.
Continuity mistake: When Marge talks to cable guy, the trees and hammock disappear.
Continuity mistake: When the family are returning from the picnic, they pull into the drive and Homer has a seatbelt on in some shots, and in others he isn't wearing it. You can't even see it attached to the side of the car sometimes.
Continuity mistake: In class, when Lisa is sitting at her desk, pondering the Jebadiah mystery, her tray of cookies and glass of milk is very visible. Then when Lisa says "The missing piece of the puzzle. I've got it." and runs out of class, the cookies and milk are no longer there.
Milhouse Doesn't Live Here Anymore - S15-E12
Continuity mistake: Right at the beginning of the episode when all the children are on the bus we can see that in front of Nelson is Bart and behind him are Lewis, Martin and Wendall. Then when the shot changes to behind Nelson, Lewis has swapped places with Bart, Bart has disappeared and some weird kid is sitting where Lewis was. (00:00:40)
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer