Continuity mistake: When Homer gets thrown out of the house by Marge and Otto walks up to him, you can see that it is Smithers and Carl standing behind Homer. Yet in the next shot when you see Homers face, you can see it is now Principal Skinner and Carl standing there.
Continuity mistake: When Mr Burns and Homer first enter the cabin, you can see the door opens with a door knob which is on the right hand side (looking from the outside). Later, after the avalanche, the door seems to open a different way, the knob has been replaced by a handle and it's on the other side.
Plot hole: When Homer is seen at work in the flashbacks (before Maggie was born), he is at his usual control panel in sector 7-G, but he only began working here when Burns made him safety supervisor in season 1, "Homer's Odyssey". Before Maggie was born he should have been working at the conveyor belt with the carbon rods, where we saw him in the first couple of episodes.