Continuity mistake: In "Desperately Xeeking Xena", as Lucy Lawless grabs the lips of the Collector, you can see a big "C" on the back of his cape. After she has thrown him across the room and he gets up, the "C" is gone. It reappears later in the fight.
Continuity mistake: When Bart is standing on the bench, Jimbo and Milhouse are standing in the front row, on the right side of the screen. But when there's the closeup (a second later), there are children shown in front of Jimbo and Milhouse and the girl with the purple hair is gone.
Continuity mistake: In "Wiz Kids", Bart stabs Montymort in his shin which is open (i.e. not covered by what he's wearing). Only a little blood pours out. Then Monty raises his shin into shot and there is not only a puncture in the leg of his clothing, but the wound is covered in blood. When he falls, and Slithers eats him moments later, there is no damage at all.
Factual error: When you see Ned Flanders put the earth back inside the hole, he puts it back in much faster than is possible. In one shot, he is only just starting to put it back in, then you see Bart who talks to himself for a few seconds, then back to Flanders, who has finished burying what is later to be revealed as the plant that he (Ned) drowned.