Revealing mistake: When Homer is imagining being locked in the jail cell and he turns around to find he is in his own home, he turns to look at his family. There is a close up shot of his terrified face, and the people in the background watching the game (I think it might be Lenny and Carl) have no eyes. The rest of their face is fine, but their eyes are missing.
Continuity mistake: When Bart and Lisa are watching TV, Bart says something like 'I've got my ticket' and pats a ticket that is inside his shirt pocket (which there is none). But later in that same scene when they are still watching TV, both the pocket and the ticket have gone.
Continuity mistake: As Homer is giving his speech to the dressed up monkeys, all of the monkeys are dressed in blue suits and you can also see there is one monkey next to the stairs on the stage. In the next shot of Homer leaving the stage there is now six monkeys, with only one wearing a suit and it is grey.
Continuity mistake: At the end just before the Simpsons say "Happy Halloween everybody" they are about to bite Lisa (and make her a vampire). Maggie has no dummy (or in America, pacifier) in her mouth, but it suddenly appears when she closes her mouth.
Continuity mistake: When Moe is going to get a plastic surgery, the surgeon draws some marks on his face. You see Moe from a side view, and the marks on his face aren't visible from that angle. However, the marks on his face suddenly appear and you can now see them from that angle.