Airport '07 - S5-E12
Continuity mistake: When Chris is sitting on the floor because Peter has taken the couch outside, his position in relation to the rug changes. (00:02:10)
The Tan Aquatic with Steve Zissou - S5-E11
Continuity mistake: When Kyle shows up to bother Chris outside Herbert's house, Chris and Kyle change position between shots. (00:05:40)
To Live and Die in Dixie - S3-E12
Continuity mistake: When we first see the Bumblescum General Store, there are two guys on the porch; one sweeping and one sitting, but shortly afterwards, the guy sitting is gone, even though there was no time for him to have moved. (00:08:05)
Continuity mistake: When Diane Simmons is announcing that she will play Anna, the five little pictures behind her change between shots. (00:11:15)
Continuity mistake: In 'Wasted Talent', near the end of the Chumba-Wumba song about Joe being in the wheelchair, the Chumba-Wumbas wheel Joe till he is about 15 yards away from the gate. Then as the shot cuts, Joe and the Chumba-Wumbas are standing right next to the gate. How did this happen? Nobody moved him. (00:10:30)
Continuity mistake: When Peter drinks the water after having all the dehydrated meals, he expands. Then in the next 'shot' he is much bigger, even though there is no time for him to have expanded further. (00:09:05)
Barely Legal - S5-E8
Continuity mistake: When Peter, Quagmire and Cleveland become cops because Joe trains them and they are all at Peter's, Joe has binoculars and is looking across the street and saying he is watching his wife Bonnie in her house. In just about every episode it is stated that Joe and Bonnie's house is right next to Peter's. So why is he looking across the street when their house is next to Peter's?
Brian Wallows and Peter's Swallows - S3-E17
Continuity mistake: After Pearl dies, Brian rubs her cheek, but in the next shot, his hands (paws) are nowhere near her cheek. (00:20:35)
From Method to Madness - S3-E18
Continuity mistake: When we first see Stewie at drama class, there is a girl with pigtails behind Olivia, but when we next see Olivia, there is a black boy behind her.
Brian Wallows and Peter's Swallows - S3-E17
Continuity mistake: When we first see Brian at the Laser Rock Show, he is sitting next to a white shirted guy, but in the next shot, he is next to a blue shirted guy. (00:04:25)
Ready, Willing, and Disabled - S3-E15
Continuity mistake: When Peter is complaining to Brian about Joe doing the cereal ad, the position of the remote changes between shots. (00:14:15)
Continuity mistake: When Lois is first using the slot machine, the symbols differ between shots. (00:11:00)
Continuity mistake: Pay attention to the items behind the police auctioneer. In the first couple of shots we see a statue of a knight on a horse to the left of the auctioneer. When the camera cuts to Peter, and then cuts back, the statue is gone. The statue is then back in the next shot. (00:03:20)
Plot hole: As evidenced by the big bar room shootout, even if they couldn't die in this episode, wounds would still show up on your body (if shot with a gun, there would still be a hole). So, when Peter jumped off the building, when he hit the ground he should have been reduced to a fleshy puddle, even if he weren't dead.
The Kiss Seen Around the World - S3-E8
Continuity mistake: At school, when Neil is wearing the shirt that shows him and Meg, himself on the shirt has black hair at first. After Meg yells at him, he has orange hair on the shirt.
Chitty Chitty Death Bang - S1-E3
Continuity mistake: When Stewie is writing in his journal, in a far shot there is a yellow space ring on his bed spread, but in a close shot there is half a green planet. (00:03:50)
Mr. Griffin Goes to Washington - S3-E3
Continuity mistake: When Peter goes to Mr. Weed's office for skipping work to go to a baseball game, he has a piece of paper in his right hand. When the shot changes, however, the paper is in his left hand.
Continuity mistake: When Stewie is just about to fly into the fan in the Griffin's living room, having just attached the antennae to Chris, a green balloon appears on his back with the other three balloons.
Continuity mistake: When Chris is sitting on his bed talking to Doug, the squares on his quilt pattern get smaller. (00:15:05)
Continuity mistake: When Stewie has been picked up by Lois and is being kissed by her, Brian freaks out. When you first see Stewie and Lois, Stewie's hands are on her shirt, next shot, they're on her arms. (00:19:40)
Answer: Lacey Chabert was the actress who originally voiced Meg in early episodes. She left of her own accord due to being in school and other acting work; Seth MacFarlane has stated there was no tension with her leaving, but it makes for a handy joke for the show.