Trivia: A Quahog is another name for a clam, thus all the jokes and places in town (like the drunken clam bar) the show makes reference about.
Trivia: One of the cutaway gags is about someone who survived 9/11 because he was late for work watching late night football. Seth MacFarlane missed his flight, which would have been one of the flights to crash into the World Trade Center, because his agent had given him the incorrect departure time. The plane was scheduled to depart at 7:45 AM and his agent had told him it was departing at 8:15 AM. By the time Seth arrived the boarding had been closed and he was told he would have to catch a later flight.
He's Too Sexy for His Fat - S2-E17
Trivia: In the shot of the Quahog Pest Control building you see a blue termite (Nibbles Woodaway) on the building. New England Pest Control in Providence, Rhode Island has the same bug on top of its building.
Trivia: During the scene with Hitler's talk show, when Hitler starts to say the show's phone number and starts shouting in German, it translates into "You're going to need a nurse".
Trivia: The prison warden in Louisiana, voiced by guest star Bob Gunton, is based on Gunton in The Shawshank Redemption.
Trivia: In the episode where Meg gets a makeover, she has an assistant on her tour bus, Miss Swan. For all those who don't know, this is a character on Mad TV played by Alex Borstein who also voices Lois Griffin (Meg's mom).
Fifteen Minutes of Shame - S2-E12
Trivia: When all the family have been replaced by actors in this episode, the actors are re-enacting the very first episode of Family Guy where Peter gets drunk and the family are eating their breakfast while Peter is lying on the table.
Blue Harvest - S6-E1
Trivia: In the episode "Blue Harvest Part 1," Peter narrates a telling of Star Wars from his point of view. When Chris is walking through the bar, we see Bender from Futurama, Coach John McGuirk from "Home Movies," The Evil Monkey from Family Guy and The Alien from American Dad sitting in the background talking to people.
Road to the Multiverse - S8-E1
Trivia: When they teleport to the Robot Chicken universe, Chris is asked how it feels to be on a major network. Seth Green, who does the voice of Chris, is the creator of Robot Chicken.
Road to the Multiverse - S8-E1
Trivia: This episode spoofs the TV series Sliders, where the main characters randomly jumped between dimensions without being able to get home.
Family Guy Viewer Mail #1 - S3-E21
Trivia: During the second act (Super Griffins), just as Mayor West says he's going to roll around in toxic waste, the crowd gives him a standing ovation. Watch the bottom center of the screen; a bald man in a grey shirt grabs the butt of the woman in a green dress next to him for no reason.
You May Now Kiss The...Uh...Guy Who Receives - S4-E25
Trivia: Adam West's enigmatic remark, "I'm the only Mayor West that's in trouble," was an oblique reference to the late Jim West, the Religious Right former mayor of Spokane, Washington and an ardent foe of gay marriage, until his career was ended by a gay sex scandal.
Trivia: Jesus's license plate is 'WWID' which presumably stands for 'What Would I Do?' a pun on the common phrase 'What Would Jesus Do?'
Trivia: When Peter picks up the TV guide with Luke Perry on it, if you pause look into the lower left hand corner and it says, "if you can read this Family Guy is on the air".
