Not All Dogs Go to Heaven - S7-E11
Trivia: Denise Crosby, who guest stars as herself, is a distant cousin of Seth MacFarlane.
Trivia: When Lauren takes Brian to the chamber to show him what she did, the corridor, the chamber, and the back-and-forth dialog about the experiment was directly copied from the scene in Star Trek II: The Wrath of Khan. Carol Marcus was taking Admiral Kirk to the Genesis Chamber.





Suggested correction: Quagmire considers the rest of them to be his best friends. He isn't drinking because they can't drink. He is complaining because since his friends can't drink - he won't drink, so he is still pissed.
It's still a plot hole considering Quagmire's age. I think the writers messed up big time.
You make a good point, but it's awkward to be that one person who is drinking while surrounded by people who can't. So, I understand the correction that was submitted above. Because his friends are not drinking, he now feels that he can't.
It's 100% a mistake. Quagmire simply would buy them alcohol the same way Brian did when they realized he could.
ctown28 ★