Continuity mistake: In the House of Erebus, right before Blade jumps off the ledge to fight Frost, you see that Karen is standing on the ledge above everything and Mercury is standing down below on the platform. But when Karen's shooting at her, Mercury is coming down the stairs from above.
Continuity mistake: When Blade gets back from the park after meeting with Frost and getting serum, he discovers Frost's men have been there, and sees Whistler. When Blade moves the tape, which is in a metal rotating stand, the stand rotates on its swivel, but in another shot it has only moved a little bit and hasn't rotated either. The tape would've been facing the other direction because the stand swivelled, but instead it remains in the same position.
Revealing mistake: When Blade is being put into the chamber so they can siphon his blood, there are straps for his neck and his wrists. He is placed into the chamber and his hands are placed in the wrist restraints, no one reaches for the neck restraint. In the next scene, the strap is around his neck.
Add timeBonita Kilpatrick
Continuity mistake: When Blade drops Karen off, she walks to her apartment and as she approaches the elevator a blonde woman walks up to its doors and stops, but in the following shot the blonde woman is now just coming into view and then stands behind the black woman instead of at the elevator doors.
Continuity mistake: When Blade and Karen are in the room of manuscripts, Quinn comes in with a load of guys. When one of the guys loses a hand by holding Blade's sword, there's blood all over the handle of the sword, yet, the next time we see the sword, there's no blood at all.