Blade's mother is still alive, and Deacon Frost is the one that bit her. Frost turns into a Blood God. Blade kills his mother and regains his strength by sucking blood from Karen and uses the blue serum to destroy Frost. The film ends with Blade in Russia.
Trivia: The original Marvel Comics' Blade was a member of a band of vampire hunters, who mainly fought Dracula (who also was a regular at Marvel). The others included Quincy Harker and Rachel van Helsing (both descendents of Dracula's enemies from Bram Stoker's novel), and Hannibal King (a vampire detective, and a victim of the original Deacon Frost).
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