Continuity mistake: In one scene after Hutch is beaten up on the bus, he has no facial injuries. Then in the next scene, they are back.
Plot hole: The whole premise of the movie is that due to a botched spell, people who happen to know that "Peter Parker is Spider-Man" are pulled inside this universe. It's a bit of a stretch already that amongst those people is...Peter Parker himself, twice over, but let's say it makes sense. The problem is that Jamie Foxx's Electro does not meet this condition; he never found out. You could say it's a retcon or it's a different universe from the original movie's, but even this cop-out explanation is negated by the movie itself when Max Dillon makes a joke that shows that he didn't know Spidey's identity or even race.
Factual error: Although it's a commonly used movie trope, cutting the brake lines on a bus would not produce the effect seen in the movie. Buses use air brakes, which by design, can operate even with substantial loss of pressure and often engage automatically if there is too much pressure loss.
Factual error: The sisters run out of fuel for the helicopter, which is then shown slamming down on the ground and essentially destroying itself. All helicopters are capable of autorotating safely to the ground in the event the engine(s) quit. Of course, that would not have been as dramatic. (01:05:15)
Factual error: Druig leads several warriors outside Tenochtitlan as it was sacked by the Spanish conquistadores, and they live peacefully in the nearby forest, for 500 years. The forest is of course the virgin Amazon forest, as captions say. Small problem; Tenochtitlan was in Central Mexico.
Factual error: Let's go by the movie geography; our planet is a big matrioska. By diagrams shown, this Hollow Earth would be by the Earth's core, thousands of miles deep. They enter from a portal in Antarctica. And yet, Godzilla later in the movie burns a random hole in the ground in HK deep enough to reach it, roars through it and Kong hears it, and the ape easily climbs it to poke back to the surface. Even admitting you can do the magic "1,000 miles in 2 seconds" warp anywhere, the scale is ludicrous.
Other mistake: On the prison computer scan of Ernst Stavro Blofeld, Blofeld's date of birth is shown as 4th July 1946, but he is only meant to be a few years older than James Bond, as seen in the photo of them together as teenagers in the film Spectre. That photo is meant to be circa 1985, and the newspaper clipping (also shown in Spectre) about Franz Oberhauser's (aka Blofeld) death in the avalanche happened when he was 16 years old. If he was 16 in 1985, then he should have been born in 1969, not 1946.
Plot hole: A core plot point (lifted by the comics) is that Venom needs phenethylamine, and the only way to get it is from brains and from chocolate. Let's just go with it and forget the fact that phenethylamine can be legally purchased as dietary supplement, which would solve every problem. So, Venom gets incredibly angry because Mrs. Chen's shop ran out of chocolates, and *therefore* they need to go raid a chicken plant to eat some chicken brain. Uh, Venom lives in San Francisco. Chocolate is sold everywhere. If Mrs. Chen ran out of it, there are hundreds of stores and vending machines that have it in abundance. The escalation does not make sense.
Other mistake: After realising they can track the mother box, Batman says they have to go back to his base to use one of his satellites to track it, and they all do so. Which completely ignores the fact that Cyborg could easily access the satellite feed directly using his abilities and display it to the others on any nearby screen in Star Labs.
Plot hole: Considering how important it is to the Analyst that Neo stay connected to the Matrix at all times, it is unfathomable that his body in the real world is unguarded. While keeping an eye on him inside the Matrix at all times is difficult, there is no reason whatsoever that he should be left alone inside his pod with no security for even a second. This is an entirely different scenario than the original 3 films where resistance fighters finding Neo was integral to the machine's plans.
Factual error: Lt. Harp is told by Capt. Leo that the Lieutenant has 56,000h of UAV flying time, That is ridiculous. Even seasoned pilots of the Military Airlift Command do not have that many hours. Drone pilots can fly up to 1,800 hours a year, and Harp hasn't been flying drones for 31 years straight.
Other mistake: The driver tells his partner that his firearm is empty, and he has no bullets in it. In the beginning he was given a loaner firearm until he could purchase his own. He's been with the company for a while now so that makes no sense. Also, for a trained professional who killed six robbers with precise accuracy it's hard to fathom he would not notice his gun weighing less. A loaded Glock 17 weighs 8.5 ounces heavier than an empty one. Plus the guards carry spare magazines, where are his? (01:20:00 - 01:22:30)
Plot hole: Dan returns from the future with a vial of toxins with him that can kill all the white spikes. He tells somebody to start mass-producing it but this information is not spread across governments or even made public, but it is the one thing they have that can prevent humanity's extinction and making people aware of that will stop the rioting.
Factual error: Dwayne Johnson is pursuing a thief. He gets into a Porsche Taycan and pushed the start button, and he can drive off. But you have to have the key fob in your pocket or bag. Porsche explains: "As long as your key is close when you grab the door handle, the system automatically checks the encrypted access code on the key. Once your code is validated, the door will unlock, and you'll be granted access to your vehicle." Dwayne had no fob, as the car was just parked.
Deliberate mistake: In the pitch dark mansion dining room, the approaching zombie's screams are instantly interrupted by silence whenever the flame from Chris' lighter goes out, and then the screams instantly resume when the light returns. While this is obvious artistic license, for the record the level of darkness would have no bearing on whether we can hear the zombie screaming.