Trivia: Throughout the show, the number 47 appears many times. There are multiple room 47's (where Syd found the Circumference in season 1 and the room in her memories from season 3, among others.), there are 47 Rambaldi artifacts, and Page 47 of the Rambaldi manuscript was the page that had Sydney's picture on it.
Trivia: Hugh Laurie auditioned for the role as Dr. Gregory House in his hotel room bathroom in Namibia. He was rehearsing his role for the film The Flight of the Phoenix and claimed that the bathroom was the only place with enough light. He also apologized for his appearance on tape before the audition as he'd just come back from filming. The fact that House has a somewhat scruffy and unkempt look, particularly his constant five o'clock shadow, has been attributed by creator David Shore to Laurie's appearance in this audition tape.
Trivia: (POSSIBLE SPOILER) When Masuka brings up the list of doctors authorized to get the M99, Dexter removes his alias note that Dexter's fake alias (used to get the M99 tranquilizer) is Dr. Patrick Bateman. Patrick Bateman is the lead character of "American Psycho". This was most likely an intentional "easter egg" of sorts within the show.Cloud203
Trivia: When Max and Temperence go out to lunch with Temperence's cousin Margaret, Max comments that the pair are "practically sisters," and later when Margaret meets Booth, Booth asks if she is Bones' sister. The actress playing Margaret is actually Emily Deschanel's sister, Zooey.Cubs Fan
Trivia: According to co-producer Tom Scharpling, the Mexican homicide cops are purposely written as parodies of Stottlemeyer and Disher, right down to their attitudes, their ranks, their suits, and Captain Alameda's mustache. Even the bumbling lieutenant's name is a little joke on Disher. Plato means "dish" in Spanish.Jean G
Trivia: Producer William Froug rejected an extremely nervous young singer/actress auditioning for the part of Mary Rachel, and recalls thinking that "I'll probably kick myself. She'll probably be a big star." He turned out to be right on both counts. The aspiring young singer's name was Liza Minnelli.Jean G
Trivia: Rick Dunkle, a Criminal Minds producer, writer, and script coordinator, has a cameo as Jonathan, the dead driver in the car that was hit by the tractor trailer, at the start of the episode. *Spoiler* Dunkie, who is a fan of Star Trek: The Next Generation, thought it would be cool to be killed by 'Wesley Crusher' who's played by Wil Wheaton, and who guest stars in this episode.Super Grover