Continuity mistake: Towards the end of the film and in the shot of the 747 as it turns to change course to Salt Lake City the company's name "Columbia" is printed on the aircraft's side on top of a large, white rectangle. After the aircraft comes to a stop on the tarmac the white rectangle is gone and the name is painted directly on its metallic fuselage.
Factual error: The 747 takes off from Washington D.C., while there's still some daylight, toward the west coast. Due to complications it's diverted to land in Salt Lake City. The Sun goes down and the plane is shown flying all night long. The Sun even comes back up before they get to Salt Lake. Really, how could it take that long for a jumbo jet to fly a measly couple of thousand miles?
Deliberate mistake: The angle of the footage of the Air Force jet (from inside the 747's passengers' viewpoint) observing the 747's damage shows the Air Force jet would be flying away from the 747 instead of flying exactly parallel as the outside footage shows.
Continuity mistake: The pilot that is flying the small plane has a plaid suit jacket on when shown from inside the cockpit. When shown from outside the plane he has a light coloured shirt on.
Continuity mistake: When the Boeing plane is about to land we are shown an aerial view of the flying plane. You can see dirt on the (wind)screen of the plane, from which the scene has been filmed. As the camera turns from left to right, you can see the dirt pass by from right to left. This is not a plane which is escorting, because when the Boeing lands there is nothing else in the air.
Continuity mistake: The pilot of the small plane that ultimately collides with the big airliner is speaking with the control tower on his radio. The identification numbers on the wings of the small airplane are not the same numbers that the pilot uses to identify his plane in his conversation with the controllers.
Continuity mistake: On the interior shots the pilot is struggling and on the exterior shots he is flying calmly.
Factual error: When the 747 finally lands it makes a hard left turn at the end of the runway. The cutaway to the passengers shows them all leaning to the Plane's left side (due to bodily inertia). For a left turn they should all be leaning to the right.
Continuity mistake: As Murdock is being lowered toward the 747 there's a shot with a POV looking at the Plane's nose from some distance. It's an FX shot, a traveling matte of the actor with a large piece of airplane against a blue screen. The foreground & background elements don't match very well. The distant landscape below is moving linearly in one direction and the aircraft is pointing in quite another.
Continuity mistake: The Beechcraft Baron strikes the 747 from the front. This comes after Air Traffic Control has told the Baron's pilot that he is "Number two for landing behind a heavy jet." Even allowing for the Baron's pilot's discomfort & disorientation due to a heart attack, how does the small plane get turned around 180 degrees and on a collision course?