Audio problem: During Selma and Bob's conversation at the dinner table in the Simpsons' house, Bob says "Although kissing you would be like kissing a divine ashtray." His lips don't move when he says "although".
Revealing mistake: When Moe and Barney are seen drinking wine at the wedding, somebody walks away with a tray. When they are drinking the animation is repeated because you can see part of the tray keeps coming on and off-screen. (Look by the bottom right). (00:13:25)
Other mistake: How can Sideshow Bob make the "I H8 BART" licence plate if there are no number keys on the keyboard? (00:04:45)
Other mistake: Near the beginning of the episode when Selma and Sideshow Bob arrive at the Simpsons' house, Bart and Lisa scream and hide behind Marge. Selma says "What the - ?" but the DVD subtitles say that Marge says it. It is shown "MARGE: What the - ?". (00:02:30)
Continuity mistake: After the dinner with Sideshow Bob, Patty, Selma and the Simpsons, the food on Bart's plate changes between shots. We first see a piece of meat with some peas, then we see two pieces of meat and some mashed potato. It changes randomly throughout the scene. (00:02:40 - 00:07:05)
Continuity mistake: Selma says she wants a separation while leaning forward with her arms behind her. Camera changes and she is stood with her arms closed. (00:18:40)
Continuity mistake: When Selma tells Bob not to worry about the cost of the wedding she has a cigarette in her hand which disappears almost instantly when she grabs Bob's hand. (00:10:40)
Continuity mistake: When Bob is telling his story about picking up rubbish on the side of the road, we see Bob in The Front of a line of people. When we see the convicts in the reflection of the trooper's sunglasses there is someone in front of him. (00:03:20)
Continuity mistake: The way the chapstick is held out for Bob in prison changes from one shot to the next. (00:04:40)
Continuity mistake: When Bart realises Selma has 1 hour to live, the remote Patty is holding disappears as the camera zooms into Bart. (00:17:50)
Continuity mistake: When Bob is litter picking, the amount of litter by his feet changes drastically between shots. (00:03:20)
Continuity mistake: During the meal at the start, the food on Bart's plate changes between shots. (00:02:50)
Continuity mistake: At the dinner table, we see an overhead shot of the table and there is a glass of milk next to Homers hand. As the shot changes, this glass is now gone from that location and moved to nearer Bart. (00:02:50)
Continuity mistake: During the wedding, look at the man with the blue hair carrying the tray with hors d' oeuvres that Homer is eating. When Homer says "Hey wiener boy. Where do you think you're going?" the man's collar changes from white to black instantly.
Other mistake: When Sideshow Bob leaves Selma to watch MacGyver, the room opposite is 350. Later when he is being taken away by the police there is a room 44. It's unlikely these two numbers would be on the same floor.
Continuity mistake: When Marge spots Krusty, from the regular view, Krusty's hand is down on the table. But from the view from the camcorder, his hand is on top of the cake. (00:14:00)
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer