Continuity mistake: When we see the extreme close up of the robotic arm picking up the blue vial, the grip is uniform and parallel to the edge of the sliver end cap on the vial. When we see the vial a second later, the arm's grip has changed and is no longer parallel or uniform on the vial. (00:02:10)
Continuity mistake: In the beginning when the the cylinders are being placed in the holders, in one close-up you can see the middle cylinder being placed and that there is no cylinder to the right of it. When it cuts a cylinder has suddenly appeared. (00:02:20)
Continuity mistake: When the person is bumped into and spills coffee on himself, the coffee stains on his shirt changes between the shots. (00:03:05)
Continuity mistake: The way the T-Virus capsule hits the ground is the same each time they show it, however when it's on the ground and motionless, the position is changes. During the flash back at the end that Spencer is having, the capsule is all over the place. However at the beginning, the capsule is just in a little straight pile on the floor. (00:03:15 - 01:09:30)
Continuity mistake: The guy states that the room is sealed and his facial expression is one of panic. Camera cuts and now he's facing a different way and his expression has changed completely. (00:05:20)
Continuity mistake: When the elevator starts to drop from floor 10, the floor indicator says 7, but a moment later it counts down from 9. (00:06:05)
Continuity mistake: When the Red Queen kills all the workers in the main office, the positions and actions of people differ from the video footage to the actual events. (00:06:35)
Continuity mistake: When the lift malfunctions, the lady has her head and arm outside the lift when she starts screaming to pull her back inside. We get one shot of her again with her head and arm outside before the shot changes to the security camera angle, and in this shot only her head is sticking out from the doors, with no time for her to move her arm (which was stuck) back inside the lift car. (00:08:15)
Continuity mistake: When the lift malfunctions, we see a shot from the security camera showing the lift going up and the lady's head being near the top of the lift door. The camera then changes to a shot from above the lift door, and we see the lift moving towards the camera, but her head is now at the bottom of the lift door again. (00:08:15)
Continuity mistake: When Alice wakes up in the shower, in one shot, you can see the shower curtain is not hanging over the edge of the shower. But when it cuts, it is. (00:08:40)
Continuity mistake: In the beginning when Alice is wiping the mirror, you can see her mouth is open. When it cuts back to her it is closed. (00:09:00)
Continuity mistake: The position of the shower curtain in relation to the floor tiles is massively different between shots. Note the tile pattern on the floor. (00:09:00)
Continuity mistake: Alice's scar on her left shoulder changes shape and redness throughout the film. (00:09:05 - 01:25:00)
Continuity mistake: Near the beginning of the movie, Milla Jovovich reads a note that has been left on the desk. She didn't write it, as they demonstrate in the film. However, when they do show the person who wrote the note composing it, the handwriting is different from that in the note from the earlier scene. (00:10:20 - 01:12:25)
Continuity mistake: In the scene where Matt pulls Alice into the mansion at the beginning of the movie and the SWAT team comes through the windows, the main SWAT member pulls Alice aside and asks for her report. If you watch the scene Alice has one arm at her side and one across her chest. A split second later it shows her reflected in the eye lenses on the SWAT member's mask and Alice has her arms crossed in front of her. Another split second later they show Alice again and her arms are in the original position. (00:13:35)
Continuity mistake: When Rain is under the train using her flashlight to see if she can see something the hair hanging across her face changes position between the wideshot and the close-up shot. (00:16:00)
Continuity mistake: When Rain tries the door on the train and fails, we see her face and her hair has 2 strands on one side of her face. Camera changes and now she's got 1 strand. (00:16:50)
Continuity mistake: On the train, just after Spence falls in, Alice takes off her wedding ring and sees on the inside: Property of Umbrella Corporation. However, after she finishes off Spence, she drops the ring next to him, and in that shot, the inside is clean; or at least the half we can see when it lies still. Such a long line would take up a lot of room on such a small ring in that size text. (00:17:45 - 01:19:05)
Continuity mistake: When the SWAT team arrives at the hive, the open an elevator shaft and one of them lights a flare with 2 hands. As the camera changes, he is now holding it at arm's length and with one hand without enough time to do so. (00:23:05)
Continuity mistake: Alice asks if Spence remembers anything from before it all kicked off. When she does, her hair is tucked behind her left ear. When the shot changes, however, it's no longer tucked neatly. (00:25:20)
Answer: Actually the T-Virus was originally meant as a cure for a genetic disorder that Dr. Ashford and James Marcus daughters suffered from. The reanimation was a side effect and James Marcus was killed by Dr. Alexander Isaacs so he could take control of it and turn it into a bio-weapon.
lionhead