Plot hole: Why does Umbrella know that Red Queen killed everyone, but not that the virus is loose? Is there no way to see into or receive data from the Hive other than Red Queen? Does every communication in or out have to be approved through her? And even if she is the sole conduit for information into and out of the Hive, her primary purpose for existing is to keep the T-virus from escaping. Umbrella THINKS that Red Queen has malfunctioned. BUT, she is working perfectly! So suppressing info that the T-virus is loose in the Hive would contradict her core programming. So why doesn't Umbrella know?
Revealing mistake: Near the end right before the end credits we see the streets of Raccoon City completely destroyed, but if you look carefully you can see the background is repeating itself street by street. The best way to notice this is to look at the firetruck right before the end. There is a firetruck, a news van and a bus. Now look to the next street on the other side of the road and the exact same cars appear there. (01:37:05)
Factual error: When Red Queen is explaining about the T-Virus they say that fingernails and hair continue to grow after death. This is not correct, While it appears that they grow, its actually down to the tissue drying out and retracting. An article on the topic can be found here: https://www.bbc.com/future/article/20130526-do-your-nails-grow-after-death A super computer that is knowle. (00:56:40)