Trivia: The picture on the computer of the hive looks like an upside down umbrella and the name of the corporation who own the hive is ... the Umbrella corporation.
Trivia: In the final scene when Milla Jovovich emerges from Racoon City Hospital into the ruined city, a newspaper blows past in the wind with the headline "The Dead Walk" - a blatant reference to George Romero's classic zombie flick "Day of the Dead" where a newspaper with the same headline blows past in the opening sequence. (01:30:00)
Trivia: The train which the heroes catch to and from the umbrella facility is remarkably similar to the train at the end of the Resident Evil 2 game.
Trivia: The scene where the licker crawls over the wall to Spence with its tongue flicking is reminiscent of the scene in the game 'Resident Evil 2' where the player sees the licker for the first time. (01:14:00)
Trivia: The group has 3 hours to make it out before the exit is sealed shut. If you beat the Resident Evil games in under 3 hours, you get souped up weapons as a bonus.
Trivia: During the 'laser fry' sequence, the team leader gets his survival knife sliced in two. The survival knife is a weapon that has cropped up in all the Resident Evil games but is as useful to your character as a toothpick. (00:30:15)
Trivia: At the end, when the scientists are dragging the infected guy away, they make a reference to the 'Nemesis Project.' In Resident Evil 3, the subtitle is 'Nemesis' because a giant Tyrant called Nemesis is chasing about the player.
Trivia: A subtle reference to the games: The name on the front of the transit train is 'Alexia'. This could be a reference to Alexia Ashford, an Umbrella researcher who appeared in 'Resident Evil: Code Veronica'. I'm also fairly certain the names 'Red Queen' and 'Hive' are attributed to Alexia's fanatical obsession with ants and the fact that the T-Virus, in the games, was supposedly discovered in an ant corpse.
Trivia: When Spence enters the secured room where the T-Virus was stored he suddenly experiences the flashback of him stealing it. This is remarkably similar to what happens to Ark Thompson in the game 'Resident Evil: Survivor'. He wakes up with no memory of who he is, fights his way into a lab complex and suddenly remembers everything before encountering a Virus experiment gone wrong. I don't think it was done intentionally but it's an interesting game reference nonetheless.
Trivia: When the zombies have just appeared and everybody is panicking, JD manages to get the door which is locked, open and a whole gang load of zombies grab him. That scene is taken from other numerous scenes of George A. Romero's masterpiece 'Day of the Dead'. (00:43:45)
Trivia: All the cast and crew (including the producer) had to undergo a grueling one week of military training (which they dubbed their 'week of hell') under the supervision of a battle hardened ex-navy SEAL. By the end most people were naturally eager to give their trainer a little of his own medicine. Miss Jovovich (Alice) did: he's the zombie she head kicks into the test-tube cabinet and then steals the gun from (before fighting the zombie dogs). What sweet justice.
Trivia: The Hive is also the name of a scenario on Resident Evil Outbreak which takes place in the Resident Evil 3: Nemesis's hospital in which you get the Anti-Virus to cure Jill Valentine.
Trivia: Fans of the games were disappointed that no game characters appeared, however they are referenced twice at the end of the movie. The newspaper seen on the stand in the foreground as Alice leaves the hospital has a sub-headline mentioning the Special Tactics And Rescue Squad police unit, and a police car next to the one Alice gets the shotgun from has the S.T.A.R.S. emblem on the bonnet.
Trivia: As an interesting homage to the movie, the latest Resident Evil game, Resident Evil 4, contains a segment in which your character must make his way down a laser swamped corridor similar to the one outside the Red Queens chamber.
Trivia: The voice of the narrator, as well as one of the surgeons at the end, is played by an uncredited Jason Isaacs, who appears in nearly all of director Paul Anderson's films.
Trivia: In the movie, the character Spence betrays the rest of the group. In the game, the character Lord Ozwell E. Spencer betrays the two scientists he worked with by stealing the viruses they created for his own company Umbrella.
Answer: Actually the T-Virus was originally meant as a cure for a genetic disorder that Dr. Ashford and James Marcus daughters suffered from. The reanimation was a side effect and James Marcus was killed by Dr. Alexander Isaacs so he could take control of it and turn it into a bio-weapon.
lionhead