Revealing mistake: As Carlos is giving his final goodbyes to Claire you can see in the background automobiles driving down the freeway. Shouldn't these roads be empty rather than having what seems to be a thriving highway? (01:10:00)
Suggested correction: Not a single car in the background.
Continuity mistake: After the Zombies are unleashed in the desert scene, we see Carlos crawling under the truck. At first his semi-automatic gun seems to be completely normal. The gun's slide and chamber are closed as if there are still bullets in the magazine or at least one bullet is chambered. But then the camera focuses on his gun and we see the gun's chamber is open - as if there are no bullets left. The gun didn't fire between shots so it's chamber should have been open in the first place. (00:58:10)
Revealing mistake: As the mutated zombies chase some of the survivors up the cement ramp in Las Vegas, watch the very last zombie just behind the girl in the tank top. He slows himself down to a fast walk when the actress starts running too slow. (00:59:40)
Deliberate mistake: During the scene where Carlos and L.J. are searching the motel, L.J. sees a zombie which turns out to be a reflection in a wall-length mirror. L.J. shoots, breaking the mirror and realizing his mistake. But, if he had been standing in front of the mirror as shown, he should have seen his own reflection standing there as well. This was done as an homage to a similar encounter in the original game. (00:24:20)
Factual error: In Las Vegas Paris and The Vencian are not next to each other. They farther part then that. Next to Paris is Ballys. (00:53:10)
Visible crew/equipment: After the first Alice clone dies in the movie and Dr. Issacs takes off his helmet, look at the scientist to HIS right(our left) you can see the boom operator in his reflective mask along with the camera operator. (00:04:50)
Other mistake: In the scene where Dr. Isaacs is in the teleconference with the Umbrella Board of Directors, there are several glasses of water sitting in front of each individual hologram. At the end of the teleconference, the holograms of the board members disappear, but none of the glasses follow suit. This tells us that the glasses of water were physically in the room with Dr. Isaacs, for absolutely no reason, given all the other attendees weren't really there. (00:17:40)
Plot hole: When the survivors arrive in Las Vegas, all that is visible is the Strip. No other buildings are seen, even though Las Vegas has other high-rise buildings that are not on the Strip, and the level of sand that has built up is not substantial enough to have buried the entire city. (00:55:00)
Plot hole: In the scene where Alice breaks into the Umbrella compound she drives the vehicle through the truck wreckage and into the fence, knocking the fence down. However, she then has time to ferry everyone from the vehicle into the chopper, stand back and watch them fly away, then walk cautiously into the shanty shack and wait for the elevator to arrive. Meanwhile not a single zombie has chased her into the now breached compound. The zombies might be dumb, but if they see food they head straight to it until an obstacle stops them and the explosion would have only killed the ones in the immediate area. The ones behind the dead zombies would have charged at them as soon as the fire died down. (01:11:00)
Revealing mistake: Near the end of the movie when they are showing Tokyo and the camera pans down through the street to Umbrella's underground HQ, you can see a rat leaning over the 'edge' of the road as it is going down. (01:23:10)
Continuity mistake: In the scene where Dr. Isaacs escapes from Alice in a AS350B Eurocopter, we see that the helicopter's landing gear has an additional iron bar that has been changed from one scene to another. When the helicopter lands in the desert, the bar is missing. So Dr. Isaacs flew away in one helicopter and landed in another. (01:04:00)
Revealing mistake: In the scene where the cowboy character is climbing the Eiffel Tower, you can see the shadow behind it only goes a few feet above where he is. Revealing that the tower is not a completed structure as shown in all of the wide shots.
Continuity mistake: When the tanker explodes that Carlos jackknifes at the end scene, the zombies that surrounded the tanker simply fall over from the explosion. However when Alice drives the H2 up to and through the wreckage the ground is clear of any fallen bodies. (01:10:50)
Other mistake: In the end fight scene between Dr. Isaacs and Alice, she bumps into the water cocoon and awakes one of her clones only to have it die a few seconds later. When she goes to cover up the body, the clone can be seen wearing a wedding ring - they don't incubate the bodies wearing jewelry in an embryonic state.
Character mistake: Alice shoots the henchmen, the black officer is attempting pull a gun from his shoe but in closeup his leg is white, then back. (01:06:25)
Visible crew/equipment: When we first see the wet floor in Tokyo, look carefully to see the reflection of the boom arm moving. (01:23:00)
Continuity mistake: When Issacs is choking Alice, she's seen to stamp and break the floorboards. Camera changes and the floor has been repaired and Alice's position has changed. (01:20:20)
Continuity mistake: When Claire approaches Alice who is watching Issacs fly away, Claire has her hands behind her back in one shot and up at her face in another. (01:05:00)
Continuity mistake: Alice steps into the entrance to the hut with her right foot in one shot and her left in the following shot. (01:12:50)
