Plot hole: When Bertha and the gang enter the Police Ordnance depot, they find an ED-209 waiting for them. It threatens to shoot them, but instead of running, they just stand there. They didn't know the girl was some kind of computer nerd that could reprogram ED-209, but for nearly 20 seconds, they just stand there.
Other mistake: After officer Lewis dies, the camera close-up shows her breathing. There is also eye movement.
Continuity mistake: RoboCop bends down to pick up the map at his feet, and he does so by scooping his hand underneath it and lifting it with his thumb and index finger, as it is lying flat on the ground. Yet when the camera angle changes to show RoboCop correcting his posture, the map is now rolled up and he is holding it in his hand, which is now in a fist position. (01:20:22)