Revealing mistake: During the scene where Frasier is dropping Charlotte off at the train station (the first time) you can see the background behind him shows that the car they are in is turning left. Yet we can see his hands on the top of the steering wheel and during this time he never turns the steering wheel.

Frasier (1993)
1 revealing mistake in Detour - chronological order
Starring: Kelsey Grammer, David Hyde Pierce, John Mahoney, Jane Leeves, Peri Gilpin
Sleeping with the Enemy - S3-E6
Character mistake: Noel Shempsky (the supposed Star Trek Nerd) attributes the quote "The needs of the many outweigh the needs of the few or the one" to James T. Kirk, when it was Spock who said it. (00:03:50)
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Trivia: When Nanette tells Frasier she's tired of playing her children's show character, she asks him if he knows what it's like to play the same character for twenty years. By this point, Kelsey Grammer had been playing Frasier for twenty years: eleven on 'Frasier' and nine on 'Cheers'.
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Chosen answer: The turkey's stuffing.