Revealing mistake: In the scene where Frasier and Lilith meet in the living room, where Frederick has created a romantic atmosphere, Frasier has a long speech about how Lilith is not going to get him back, ending with "I need to be finessed!" and Bebe Neuwirth goes out of character and begins to giggle, before she quickly covers her mouth and pulls herself together. Though Lilith might have found Frasier's comment amusing, it would definitely not be in character for her to giggle like that.
To Thine Old Self Be True - S7-E20
Revealing mistake: When Reagan drops her bag in the hallway when she is talking to Frasier, a lettuce rolls towards him. It didn't fall from her bag: if you look closely you can see it was tossed into the frame from just outside the camera view, obviously to ensure that it would land at Frasier's feet for the comic effect of him kicking it back to her.
Answer: It equals the record of James Arness of "Gunsmoke" for the actor who's played the same part on TV NOT in a soap opera. If you include soaps there are two main contenders - William Roache, who's been playing Ken Barlow in "Coronation Street" in the UK since 1960. Don Hastings has been playing Robert Hughes in US soap "As the World Turns" since 1960 as well.