Continuity mistake: When Jill Valentine and Angie are running from the dogs after turning on the gas, Jill kicks the left side of the double doors open. However, when she turns around to see if the match ignited the gas, she has the right door open. When Jill Valentine realizes Alice light a cigarette she starts running, again out of the right side of the door. (Looking at the doors from the kitchen to the cafeteria). (00:56:00)
Continuity mistake: Near the end, at the chopper crash site, the Umbrella man lifts the corner of the sheet covering Alice's body. From the high zoomed out shot, the guard is facing the waterfall, while the next shot he is facing the body. (01:18:50)
Continuity mistake: When Alice slides on the floor, she shoots up a hole in the wall and goes down it, dislocating a finger on her left hand in the process. In the next shot she straightens it out, and the finger is on her right hand.
Continuity mistake: In the DVD, at the climax, just prior to when Alice is forced to fight Nemesis, she has a conversation with Thomas Kretschmann (the dude with the leather coat). During the conversation, one shot shows Alice with blood trickling down her neck and some bruises on her face after she previously had no injuries. Moments later, her face is back to normal. Later, during the fight with Nemesis, you see that that is where she sustains her injuries.
Continuity mistake: Just before Nemesis starts shooting at Alice after shooting at Valentine, the counter on his gun shows 0000 rounds left. (00:42:10)
Revealing mistake: Resident Evil Apocalypse was shot in Toronto and the filmmakers wanted to use the city surrounding the CN tower to be Raccoon City. They edited out the CN tower, however they missed a brief glimpse at it. It's shown really quickly in between when Angie's vehicle crashes and when it stops. (00:05:25)
Continuity mistake: Watch the scene where Alice almost pokes the scientist with the pen. In the close up shot of the guy's face, she almost poked him in his left eye. In the far shot, the pen is being pointed at his right eye. (01:23:30)
Continuity mistake: When Nemesis blows up the STARS sniper on the roof of the theater, the size of his rocket launcher changes drastically. (00:37:55)
Factual error: When the nemesis creature fires a rocket-propelled grenade down the laundry chute/garbage chute at Alice, she protects herself from the blast by a plastic cart. When Alice tips the cart it warps and bends, and even more obviously when Alice leans on the side. There is no way this would have worked, the plastic cart would have been destroyed along with her.
Continuity mistake: When Alice escapes from Nemesis falling into the garbage, she shows both hands with her fingers in good condition. Yet in the next shot, she has a very badly broken finger. (00:45:30)
Visible crew/equipment: A boom mic operator wearing a white shirt is seen reflected in the door that the female scientist opens, when the Umbrella personnel pick her up, as part of their extraction procedure. He is visible as the door is opening and very faintly when it is closed. (00:04:00)
Continuity mistake: When they're in the school and they split up, Terri walks into the classroom and the map at the front of the classroom has bloody hand prints on it. When Jill Valentine walks into the same room later, there are no hand prints on the map.
Suggested correction: It's two different maps on two different walls.
Continuity mistake: When the scientists are standing at the entrance to the Hive, one of them opens a small transmitter, reflected in his mask, with its antenna pointing over 45 degrees. When it cuts, the antenna is pointing almost horizontally. (00:02:45)
Plot hole: After Dr. Ashford was shot, he stayed down the whole time that Alice fought with Nemesis, they fought with Umbrella, and after they took off. How is that possible? According to all the other times they've been shot, and with the t-virus in their bloodstream, they reanimate almost ten minutes later -- not when the director wants.
Suggested correction: The doctor reanimated after roughly 5-10 minutes, just like every other one does... as stated in the error. Plus convenient timing isn't a plot hole.
Continuity mistake: In the church, Peyton asks Terri about her video camera. She has it raised to shoulder height. Cut to her face and the camera's gone. The next shot is through the camera and shows the same view of Peyton we could see before over her shoulder, so she didn't move it. (00:20:45)
Continuity mistake: When Alice has refused to finish Nemesis off, she stands alone. Mr. Bad Guy tells Nemesis to kill her, and two Umbrella men suddenly appear out of nowhere beside her.
Continuity mistake: In the church scene, Alice blows up her motorcycle with two shots of her Colt .45's. During the shot of her back, she already starts with holstering her guns, her arms are already halfway there when the shot cuts. Then, there is a quick shot of the explosion, and in the next shot her arms are straight again, in the position where they were when she took a shot at her bike. There is no reason or time enough to do that.
Continuity mistake: When Alice is asleep and submerged in the water tank her body is in a fetal position. She wakes up and moves around. The water is then drained from the tank, but she's still in the exact same fetal position. (01:20:45)
Factual error: In the cemetery scene about 1/4 through the movie, you see a corpse with meal worms eating its head. It's a cemetery, not a bait shop. What, is the corpse a fisherman? I am pretty sure you would never see this in real life. Meal worms eat mostly bran, fruit and vegetables and fish eat them. Worms and maggots yeah, but not mealies.
Visible crew/equipment: When Nemesis shoots the guy on the roof of the theater, you can see a machine that shoots out fire.