Continuity mistake: In the scene where the Nemesis kills the 13 S.T.A.R.S members, after it blows up the sniper on the roof an additional S.T.A.R.S member can be seen outside the building on the right who wasn't there earlier. He then disappears shortly afterwards.
Revealing mistake: Nearly at the end, the scientists find Alice's body at the waterfall, one of the men lifts up the cloth to take a look at her face. Her face is badly burned on one side and she is pronounced dead. However, take a look at the left side of her neck, you can see her either gulp or take in a quick breath of air. (01:19:05)
Factual error: When any character's automatic pistol runs out of bullets, the slide doesn't lock open. All the weapons shown are of a type which should.
Revealing mistake: At the beginning, when one of the black trucks has an accident, whatever is making the dramatic sparks is still running when that part of bodywork is off the ground. (00:05:25)
Continuity mistake: At the end of the film when Alice gets her memory back, she grabs a pen and points it very close to a man's eye, then the camera changes shot still looking at Alice and the man but the pen is much further away from the eye than before.
Revealing mistake: When Alice fixes her broken finger, you can see that the finger (and the entire hand) is made of rubber. This is even more obvious on the Blu-ray.
Continuity mistake: After the gas explosion in the school, Angela reveals that Alice is infected. The woman cop asks "When were you gonna tell us that?" and the next shot shows Alice with burns/blood on her upper left arm. In the next shot as Alice goes to sit down, the severity and position of the burns/blood changes. (00:56:50)
Continuity mistake: When the girl is being chased by the zombies (just before we meet Carlos) the keypad for the door is right next to it. When she tries to enter the code, it is suddenly next to the small grey box. (00:09:30)
Suggested correction: It's next to that small gray box (appears to be a light switch) in every shot. At no point is it anywhere different.
Continuity mistake: Watch the left side of the mouth piece in Alice's mouth when she is in the tank at the end. In the shot up close to her left there is a plastic support going up, in the next shot of her right the support is pointing down, and after the scientist says "can you hear me?" and the shot is close to her, the support isn't even there. (01:20:30)
Revealing mistake: In the early aerial shots of Raccoon City, look to the left of the screen and you can see the CN Tower, a very recognizable landmark that is definitely in Toronto, not Raccoon City. This is due to the fact that film was shot in Canada. (00:05:25)
Continuity mistake: Toward the end, Major Cain storms aboard the helicopter, shouting "Why haven't we taken off, yet?" The shot switches to LJ (Mike Epps)in one of the pilot's seats. As he says, "Because I normally drive Cadillacs" he punches out at Cain with his left hand. In the reaction shot, however, as Cain flies backward, the punching hand is LJ's right hand. (01:12:55)
Visible crew/equipment: When the SUV is struck by the large truck and is pushed along while upside down, a camera mount can be spotted (helps if you use slow motion) and also, a tow truck can be seen actually pulling the SUV along the street. (00:05:15)
Continuity mistake: Nemesis has an ammunition counter for his Vulcan cannon. When Nemesis is shooting at Peyton on the bridge, his counter stops at 3997 rounds. Almost immediately he begins shooting at Jill, but now the counter reads 3688. (00:43:20)
Suggested correction: The counter doesn't "stop" at 3997, the audience's POV changes while Nemesis is still firing, and the counter is last seen at 3978. The camera switches back to Nemesis' HUD roughly 5 seconds later when it is at 3688. Considering Nemesis is firing for some of the 5 seconds between when we can see the counter, and that miniguns can fire 100 rounds per second, none of this is impossible or even implausible.
Deliberate mistake: When Alice first fights the Nemesis, she attempts to jump over a fence and make an escape. When she lands on the police car, Nemesis fires his RPG at her. If you look closely, the rocket passes magically right through a chain link fence without touching it at all. (00:44:40)
Suggested correction: Rocket made a big hole in the mesh. Clearly shown.
Continuity mistake: A zombie hits its head on a tombstone, which falls over. In the next shot, it's upright again. (00:32:40)
Suggested correction: Could easily be another zombie and another stone.
Factual error: The sniper on the roof who is casually picking off zombies hand loads his rifle after every shot. The rifle he is using is the AWP Magnum which has a spring loaded 10 round clip and a breach that cannot be hand-fed ammunition. (00:36:30)
Suggested correction: Ammo can be manually loaded, it's inefficient but not impossible.
Continuity mistake: When Alice and the group are going to raid the Umbrella guards and steal the helicopter, one of the men looks through binoculars with night vision. He looks at the helicopter, then looks to the right of the helicopter, yet in the next scene a second later, his head is in the same position as it was when he looked at the helicopter, before he looked to the right.
Continuity mistake: As Alice is attacking the guards around the helicopter with the batons, she switches from holding them low to holding them high between shots right after she knocks down the last guard. There isn't enough time or any reason for her to do so in the second offscreen as the others arrive. (01:04:15)
Revealing mistake: Near the end of the film when the zombies are shuffling up what looks like a parking ramp towards the escape helicopter, in several shots it's painfully obvious that some zombies don't have any makeup at all and a good portion are walking normally, unlike their shuffling comrades. One with blonde hair is even using a handrail. (01:15:20)
Continuity mistake: At the surplus store as a hand picks up a weapon, it is clear that the person is wearing jeans. The next shot is of a person wearing a lab coat and after that we see Alice getting dressed. (00:18:25)
