Visible crew/equipment: When Melissa dodges the truck that has fallen from sky and Dusty rushes to open a door and help Melissa get out of the truck, the reflection of a camera is seen in the bottom right corner of the truck window. As they move out and pan to the right, you can see a reflection of the same camera and cameraman at the bottom right corner of the truck door as they move away. (00:33:50)
Visible crew/equipment: As Jake approaches the house after the van drives off, it looks like a crew member got caught at the side of the house and moves back as Jake is taking camera footage. (01:03:25)
Continuity mistake: When Norman is getting ready to test himself, he lies down on the bed, fastens himself in and the doctor goes to the computer. However, when it shows him being brought in to the chamber he has several electrodes connected to his chest and head. (00:15:20)
Audio problem: After the aeroplane crashed, a dinosaur stepped over it and the windows shattered making the typical sound of made-of-glass things when broken. They are made of plexiglass (a sort of fibrous plastic).
Revealing mistake: In one shot when the boat is pulling away from the waterfall, you can clearly see that the shot is the same one they used earlier in the movie. The water from the waterfall now is going up the cliff! They have just put it in reverse.
Continuity mistake: The tyres on the crotch rocket motorcycles they were riding kept changing from knobbly tyres to road slicks, back and forth depending on what terrain they were on. Easiest to see when Ethan skids on the road to avoid the white van - clear shot of slick tyres - then about 30 seconds later they're on the dirt, he skids into the old car and you can easily see that he's got off-road tyres front and back.
Revealing mistake: When Carl is being dragged away by the demons, you can see the cable line that he's attached to. May be fixed on DVD.
Plot hole: An important plot point (in the book and the film) is that Charles Calthrop - thought to be the Jackal, at that stage - played some mysterious part in the 1961 assassination of Rafael Trujillo, the dictator of The Dominican Republic, and rumours of his involvement came to the attention of MI6 and Special Branch, leading to the accidental exposure of the Jackal's false passport. In fact there is no mystery at all about the assassination of Trujillo and there were no shadowy foreigners involved. It was organised by Trujillo's own senior aides, amongst them General Juan Tomás Díaz, Antonio de la Maza, Amado Garcia Guerroro and General Antonio Imbert Barrera. The gunman was later identified as Luis Aniama Tio. All the conspirators except Tio were arrested, tortured, and shot. There was no panicked evacuation of foreigners who were involved with Trujillo's regime, and no reason for them to be concerned - the government did not fall and Trujillo's brother Hector took over as President, ruling in a brutal and totalitarian manner for a further eight years. Any rumours of a mysterious Englishman would have been dismissed out of hand and would not have made it onto even the lowest level filing system anywhere in Whitehall.
Factual error: Fitch, who professes qualifications in biology, genetics and biochemistry, says that they made Sil female because she's a natural predator and so she'd be more docile. He should retake his finals. In every single species of predator on earth - every single one - the females are the hunters, aggressors and killers. The males may be socially dominant but they are the 'docile' ones. There are no exceptions - and no human DNA was used to create Sil - they used synthetic DNA based on the instructions transmitted to them.
Continuity mistake: In the British Museum, when Rick and Ardeth are saving Evie, Rick gives her a .45 pistol and they start to shoot the guards, her pistol fires once and the slide locks back meaning the pistol had no ammo, but she keeps firing as if the magazine was still full. (00:39:47)