Visible crew/equipment: When Pee Wee is chaining up his beloved bike you can see the long chain coming up through the bottom of the bike box. Full screen version only. (00:13:40)
Other mistake: Murphy lands the helicopter on a railway line so an oncoming train will destroy it completely, and this happens exactly on cue with huge, dramatic explosions and flying debris. Apparently the train driver doesn't think this is important enough to interrupt his busy schedule - he doesn't stop the train. We do not hear brakes being applied - the wheels would make a noise like the sky coming down - and the train doesn't slow down at all - it just keeps on going.
Continuity mistake: When they finally arrive at the bottom of the sewer, Eddie's bandage is on a different cheek. (01:59:00)
Continuity mistake: In the exterior front shots of Elliott's house there are some significant changes to the landscape in different shots. For instance, the two lampposts at the bottom of the driveway change to an entirely different style in some shots, and the huge garden boulders repeatedly vanish and reappear. Also, note when Michael takes off on Elliott's bike to go search for ET, the in-ground lamppost that should be beside the mailbox has vanished, but it reappears when all the government agents are setting things up outside the house.
Factual error: Twice in the film it is made clear that the Pym particle works by reducing the space between atoms in order to shrink an object, and by increasing it to enlarge them. This means that the object will weigh the same, whether shrunk or enlarged - it cannot be otherwise. A 90kg man the size of an ant would punch a hole through any surface upon which he stood (and couldn't ride ants), Doctor Pym has been walking about with a 60 tonne tank in his pocket, Darren Cross lifts a full grown sheep between finger and thumb, and the supersized Thomas The Tank Engine would be far too light to crush the police car (in fact it would float harmlessly away as it would probably weigh less than the air it displaced).
Other mistake: When Adam comes in and says "when I woke up this morning, the pain was gone", Connie is mouthing his lines behind him.
Continuity mistake: After Mark is found, he runs into Kate's arms and hugs her and her sunglasses fall off her head, but then in the very next shot they're back on her head perfectly. (01:24:50)
Continuity mistake: The tyres on the crotch rocket motorcycles they were riding kept changing from knobbly tyres to road slicks, back and forth depending on what terrain they were on. Easiest to see when Ethan skids on the road to avoid the white van - clear shot of slick tyres - then about 30 seconds later they're on the dirt, he skids into the old car and you can easily see that he's got off-road tyres front and back.
Plot hole: Lucy jumps from the airliner and flies her hang-glider straight to Eduardo/El Macho's Cinco de Mayo party to find Gru. How did she know Gru would be there? He had no intention of going and only did so after he was pestered into it by the girls on the very night of the party, so he couldn't have told her himself. Shouldn't she have gone to his house instead? (01:09:50)
Continuity mistake: If you look carefully at the monster (Frankenstein) you will see that his face is different in the ending scenes. The reason is, during the movie you see the monster take the woman doctor and throw her out the laboratory window. You then see the monster kind of stumble, which he really did and broke his ankle. So in the final scenes they replaced Lon Chaney Jr. as wolfman with a stuntman, and Lon Chaney Jr. finished the movie as the monster.
Continuity mistake: When they are looking at the house and they get out of the car, the one man on the passenger side leaves his door open. When they walk to the side of the house and come back to the front, you can see the car in the background and the door is shut.
Factual error: Whenever the fire extinguisher is activated for a jet engine, that engine becomes inoperable. In the movie, the co-pilot first activates the extinguisher for the left engine, and 30 seconds later, for the right engine. At that point, both engines should be shut down. However, the engines are still operating (and revving up) and Whitaker even asks Margaret to apply full power, which is also audible. (00:23:00)
Revealing mistake: When Carl is being dragged away by the demons, you can see the cable line that he's attached to. May be fixed on DVD.
Continuity mistake: In the final battle, Wasp and Ant-Man are in the van trying to get the quantum tunnel operational. We cut back to the fight and we can see Ant-Man there too, fighting in his giant form. (02:22:20 - 02:23:00)
Plot hole: An important plot point (in the book and the film) is that Charles Calthrop - thought to be the Jackal, at that stage - played some mysterious part in the 1961 assassination of Rafael Trujillo, the dictator of The Dominican Republic, and rumours of his involvement came to the attention of MI6 and Special Branch, leading to the accidental exposure of the Jackal's false passport. In fact there is no mystery at all about the assassination of Trujillo and there were no shadowy foreigners involved. It was organised by Trujillo's own senior aides, amongst them General Juan Tomás Díaz, Antonio de la Maza, Amado Garcia Guerroro and General Antonio Imbert Barrera. The gunman was later identified as Luis Aniama Tio. All the conspirators except Tio were arrested, tortured, and shot. There was no panicked evacuation of foreigners who were involved with Trujillo's regime, and no reason for them to be concerned - the government did not fall and Trujillo's brother Hector took over as President, ruling in a brutal and totalitarian manner for a further eight years. Any rumours of a mysterious Englishman would have been dismissed out of hand and would not have made it onto even the lowest level filing system anywhere in Whitehall.