Continuity mistake: When "The Leader's" car drives by, trailing a cloud of dust, the dust doesn't appear on the people's robes until the cloud clears away.
Continuity mistake: When Homer is fishing, the colours of the things on his hat switch places between shots.
Continuity mistake: When Frink collapses at the table, his sleeves are green. When it cuts to a wide shot, they are yellow.
Continuity mistake: When Bart and Lisa are in the compound, just before Bart gets brainwashed, the bags that were behind Lisa disappear. Homer and Marge were on the other side of the room, so they couldn't have picked them up.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer