Continuity mistake: Five Characters In Search Of An Author: After you have reached the interior of the mansion, try and run up a staircase as Bart. If you change the camera angle to an aerial shot and walk up the staircase, a chandelier will appear. If you do nothing the chandelier will just vanish from shot, despite not having moved.
Character mistake: Big Super Happy Fun Fun Game: During the battle between Homer and Lisa and Sherri and Terri (who are both female), just as Lisa unleashes Linguo, Lisa says "Linguo, fix his grammar for good." In this context, it should be "her" or "their."
Continuity mistake: Grand Theft Scratchy: The woman in blue gets crushed by the huge heart fixed onto the sweet store. This heart was never visible during the wide shot at the start of the cut scene.
Continuity mistake: Bargain Bin: When Homer places the Duff can on the computer DVD player, the can falls over and spills on the keyboard. In the next shot, the Duff can vanishes.
Revealing mistake: Invasion of the Yokel Snatchers: On the Wii version, just as Homer and Bart are about to be sucked into the spaceship, a car on the ground can be sticking through part of a damaged wall. As Homer and Bart are sucked into the ship, the car then lifts out of the ground and fades through the wall without damaging it.
Continuity mistake: Enter The Cheatrix: After Bart and Lisa break into Frink's basement, they discover a Rift Portal. The first shot shows the "DO NOT USE" sign a foot above Bart and Lisa's height. But as Bart walks into the portal, the sign is suddenly located at the same height as Bart.
Plot hole: Principal Skinner got arrested in "Bartman Begins" for getting the bullies to steal from the museum. Yet in "Mob Rules" (which takes place on that same day), he is seen outside Springfield Town Hall instead of being in jail. Marge did break Snake out of jail earlier in the level, but Skinner was never seen in jail.
Continuity mistake: Around The World In 80 Bites: In the ending cutscene, the losing contestants have to clean up. There's hardly any mess when they start cleaning. But the place is suddenly filled with mess when Comic Book Guy says "Less references, more mopping" to Willie.
Continuity mistake: Bartman Begins: After Bart flies onto the seal forming the bridge, a cutscene is then shown of Homer and Bart standing next to a glass wall witnessing the bullies stealing the artifacts. When it returns to the game, Homer and Bart are back on the seal.
Bug: The Land of Chocolate: To end the level, the game will need the player to smash all of the chocolate rabbits. If there are two left and you destroy one of them, the level will still end even with one of them still alive.
Continuity mistake: Big Super Happy Fun Fun Game: When Milhouse is about to give the key card to Homer and Lisa, he extends his arm to hand it to them and puts his arm in a bent position. In the next shot, his arm is fully extended, with no visible bend.
Continuity mistake: Lisa The Tree Hugger: Lisa takes the The Simpsons Game manual off Bart. After Bart says "Can we skip this level?", Lisa starts talking to Bart and the manual has disappeared. There was also nowhere for Lisa to put the manual.
