Other mistake: Towards the end when Dennis Hopper is on the subway train with Sandra Bullock, he has a gun in one hand and the detonator in the other. However, when the camera cuts to a close-up of him handcuffing Sandra to the pole, both hands are empty. If he took his hand off the detonator, the explosives attached to Sandra should've exploded, but they didn't. In the next shot, both items are back in his hand.
Other mistake: As the first bus explodes on its way from the cafe, we can see a blonde pedestrian casually walk past a window with her ears covered. At no point does she even stop to glance at the burning wreck. It seems (from her perspective) as though the explosion were merely an inconvenient loud noise and nothing worth noticing.
Other mistake: Just after the police close the roads in front of the news crews and the black police chopper lands in the road. There is a scene where the bus passes under a flyover with a police escort but the police car in front of the bus nearly stops, making the bus brake hard and nearly stop, bringing it well below 50 mph.
Add timeMark Gibbs
Other mistake: During the scene where Jack and Annie escape from the bus using the hatch door on the bus floor, they lay on it sideways holding on to each other. If you had a chance to look at the bus from various other camera shots during the film the gap between the undercarriage and the runway was too small for them to do this, the rear bumper also seems to hang lower.
Other mistake: When the safety cable goes taut and stops the falling elevator, a woman standing in the corner is shown to fall through a hole in the floor. However, the hole in the floor was plainly visible in the bottom of the elevator as it was falling. As the hole was more than wide enough for the woman's legs to fall through, she couldn't have been standing in that corner as it was falling.
Other mistake: The bus is supposed to maintain a speed higher than 50 mph to avoid disaster. But at one point where the baby carriage full of cans falls to the pavement and starts tumbling we can see part of the bus in the background, slowed to a crawl and certainly not traveling at least 50 mph.
Other mistake: Tuneman's Jaguar has 127 miles accumulated on the odometer (brand new, effectively). It comes into view once when Jack notices that the bus is quickly decelerating to a very dangerous speed. However when we see Jack grab a mobile phone, there is excessive wear and tear on the center console beneath it, to the point where complete deterioration has occurred in the high stress areas - characteristic of a much older vehicle. Hard to believe such a thing would happen to a vehicle of that caliber in such a short length of time. So it's possible that the odometer we see moments before isn't even from Tuneman's Jaguar at all.