Revealing mistake: When Stewie and Brian appear in the future and watch the Griffin family in the future, the pole of the staircase Brian is holding is differently animated to the rest of the staircase. (00:13:25)

Family Guy (1999)
1 revealing mistake in season 10 - chronological order
Starring: Mila Kunis, Seth Green, Seth MacFarlane, Lacey Chabert, Alex Borstein
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Suggested correction: Quagmire considers the rest of them to be his best friends. He isn't drinking because they can't drink. He is complaining because since his friends can't drink - he won't drink, so he is still pissed.
It's still a plot hole considering Quagmire's age. I think the writers messed up big time.
You make a good point, but it's awkward to be that one person who is drinking while surrounded by people who can't. So, I understand the correction that was submitted above. Because his friends are not drinking, he now feels that he can't.
It's 100% a mistake. Quagmire simply would buy them alcohol the same way Brian did when they realized he could.
ctown28 ★