Continuity mistake: When Rango is stranded in the middle of the road, he is clutching a drinking glass in his left hand. For the rest of the scene (starting from when he molts), the glass switches to his right hand.
Directed by: Gore Verbinski
Starring: Johnny Depp, Bill Nighy, Alfred Molina, Ray Winstone, Timothy Olyphant, Ned Beatty, Abigail Breslin, Isla Fisher, Harry Dean Stanton, Stephen Root
Genres: Action, Adventure, Animated, Comedy, Family, Western
Continuity mistake: When Rango is stranded in the middle of the road, he is clutching a drinking glass in his left hand. For the rest of the scene (starting from when he molts), the glass switches to his right hand.
Other mistake: When Rango is loading his revolver during the stand-off, he loads the bullets on the right of the revolver, however, the chamber is hanging from the left of the revolver.
Trivia: At the beginning of the movie when Rango is flying around on the highway he lands on the windshield of a red car with a bald man smoking a cigarette, that is a reference to the movie Fear and Loathing in Las Vegas in which Johnny Depp stars.
Answer: TV Tropes mentions that the big eye might be an enormous alligator, because alligators are known to live in sewers.
Alligator eyes are different from what was shown in the movie.