Rango: We can control it! Like a monkey's bladder!
Rango: Stay in school, eat your veggies, and burn all the books that ain't Shakespeare.
Rango: I'm going to slice your face off and use it to wipe my unmentionables!
Rango: I think the metaphor broke my spleen.
Beans: Get your slimy webbed phalanges off my boots!
Elgin: One time I coughed up an entire tribe of pygmies. They started lookin' at me weird.
Willy: I remember them. They was quite friendly.
Spoons: I found a human spinal column in my fecal matter once.
Answer: TV Tropes mentions that the big eye might be an enormous alligator, because alligators are known to live in sewers.
Alligator eyes are different from what was shown in the movie.