Continuity mistake: When the wolf scares Mina in the movie theatre, her hat switches back and forth from being forward on her head, to being tilted back. It does this in about 5 shots. (00:53:40)
Continuity mistake: When Dracula stabs the cross and blood pours out of it, in one shot it is slowly creeping towards Mina's dead body and in another shot it is rushing past her and in the next shot it's slowly creeping again. (00:05:20)
Audio problem: When Dracula and Mina first meet on the street they begin to speak. Dracula's voice has not been dubbed during the first sentence or two. Then in mid stream his voice changes from a high pitched regular rehearsal voice to the heavily accented Romanian voice used throughout the rest of the picture. (00:45:20)

Visible crew/equipment: After the hairy beast Dracula attacks Sadie Frost, Winona Ryder comes to get Sadie in the garden maze. While they're walking back, you can see the camera's shadow on Winona's back. (00:43:35)
Continuity mistake: In the last scene, when Mina Harker lays Dracula's body in the cathedral's altar, she kisses the vampire's lips and he turns into his human self. His face is covered with blood down from his nose, but after the kiss Mina's lips have no sign of blood. (01:58:45)
Revealing mistake: In the chase scene near the end, when Dracula is hiding inside an earth-filled coffin in the gypsy carriage, you can clearly see the tip of one of his rubber-made finger extensions bending.
Continuity mistake: When the peasant woman gives Jonathan the crucifix in the carriage, the chain falls over the side of his palm. When he opens his hand to look at it, the chain runs between his fingers.
PhoenixVisible crew/equipment: When Dracula is going to enter Lucy's bedroom for the last time, an unseen force knocks Cary Elwes backwards. Upon careful inspection, you can see a wire or cable pull him back.
Continuity mistake: When the brides of Dracula come out topless to suck Jonathan's blood, Dracula breaks in, furious, and the brides are suddenly fully clothed. (00:32:45 - 00:34:25)
Revealing mistake: When Dracula first bites Lucy, the wounds can be seen on her neck before the actual bite. (00:40:35)
KylanthaRevealing mistake: When Arthur is guarding Lucy, just before he sees Dracula, a female voice can be heard saying "Now", cuing him to turn his head. (01:16:20)
KylanthaSuggested correction: While it is possible to interpret the sound as a woman saying "now", the manner in which it would be said makes it very unlikely it was someone on set giving a cue. It is long and drawn out, more like "neeoow." Someone on set would probably say and concisely "Now." It is far more likely this is another place in the movie where many sounds are overlaid for eerie effect. If I had to pin it on something exactly I would say it represents Lucy responding to Dracula's presence with an inviting sound.
Continuity mistake: During the crypt scene, when Lucy's body is interred, the shots of her in the glass coffin and later rising out of it, show dramatic difference in the depth of the coffin. (01:24:55 - 01:27:05)
Revealing mistake: In the crypt scene, Van Helsing, as you can see, cuts off Lucy's head. But when the head pops off, you can see that where there should be blood, guts, flesh, etc., there is only some white blankness. (01:27:45)
Visible crew/equipment: In the scene where Lucy is done in by Dracula in wolf form, as she dies, blood is exploded into the room by "supernatural" forces. If you look in the torrent of blood, you will see the gas, I assume carbon dioxide, from the special effect cannon appear and evaporate. (01:21:00)
David8366Continuity mistake: When Van Helsing breaks the news to Quincey after reading the "Vampyr" book, as he says, "Yes, we may still save her precious soul", he's gripping Quincey's coat, and Quincey's left arm is down, but in the previous shot, Van Helsing's arms were down by his side, and Quincey was holding onto the hat on his head. His other arm changes position as well. (01:14:15)
KylanthaFactual error: At the beginning of the movie, it was stated that Constantinople was captured by the Turks in 1462. The Turks actually captured it in 1453.
Factual error: At the cinematograph, Mina says to Dracula, "How can you call this science? Do you think Madame Curie would invite such comparisons? Really!" The movie takes place in year 1897, but Marie Curie's works weren't published until 1898. (00:49:30)
KylanthaContinuity mistake: After Dracula opens a vein in his chest, his hair alternates between being over/behind his shoulder, depending on the camera angle. (01:36:15)
KylanthaContinuity mistake: When Prince Vlad tilts the baptismal font, the stains of Elisabeta's blood on the floor changes position between the overhead shot and the close-up, easily seen from the cracks in the floor. (00:04:10)
KylanthaContinuity mistake: When Keanu Reeves is being seduced by Dracula's brides, Monica Bellucci rips open his shirt, but in the previous shots, his shirt is already open. (00:31:45)
Kylantha