Revealing mistake: In the scene close to the end when the turtles are fighting the foot soldiers on the fire escape (directly before the scene where Mikey ducks under the foot soldier's axe), Raphael thumps a foot soldier on top of his head and then rams the soldier's head into the stairwell. The only problem is the soldier's head misses the stair by about a mile. The sound effect of impact is there and the soldier even holds his head as if he were hurt.
Revealing mistake: In the scene where Raphael is thrown through April's skylight after being attacked by a few dozen members of the Foot, the other Turtles and April check on him. As Donatello and Leonardo look him over, they lean on his shell, bending it with great ease even though a turtle's shell is supposed to be almost as hard as rock.
Audio problem: At the climax of the film when the Turtles are about to face Shredder for the first time, Raphael says, "I got him" and then runs to fight. When Raphael falls to the ground, his pair of Sai hit the ground but make no noise. There should be a metallic sound against the rooftop. (01:19:00)
Visible crew/equipment: After Casey takes a golf club and drives Master Tatsu into a pile of boxes, a camera lens hood is visible on the left side of the screen. It can be seen again in a later shot right before Casey and Danny carry Splinter away (full screen version). (01:14:40 - 01:15:50)ryguy_1983
Revealing mistake: A lot of times in the movie, when the turtles' mouths are wide open, you can see the cast. An example of this is the scene when Raphael wakes up in the bath tub and Leo hugs him. When Donatello tilts his head back and laughs you can see eyes, a nose, and a mouth within the mouth of the costume.Jason Voorhees
Visible crew/equipment: Just before the ceiling collapses on the antique store a boom operator can be seen on the right hand side of the screen.
Continuity mistake: After Raphael has a fit and walks out of April's apartment, he goes up on the roof to vent his anger for a while. Pretty soon, Casey spots him from another rooftop several buildings away while tuning a radio. As Casey looks out at Raphael's faint image in the distance, pay close attention to the background as well as the white building Raphael is standing on (you can notice the Empire State Building among other landmarks). When Casey grabs some binoculars to take a better look, Raphael can be seen resting on a brick ledge. In the following shot Raphael looks out at the city towards Casey's vantage point, but from Raphael's position, the Empire State Building - as well as the white building where he was venting just moments before - are visible on the skyline. Somehow Raphael has managed to relocate to another building's rooftop between shots. (00:38:15)ryguy_1983