Continuity mistake: Tony Trihull appears when Finn McMissile begins chasing Professor Z. It also shows when Tony uses his magnet. When it is used, Finn's equipment are pulled by the magnet, which includes his bullets. Those bullets are black when all of them were going out. However, when they are pulled onto the magnet they are grey.
Factual error: In one of the first major scenes where Matt Franklin and Tori Frederking are being introduced at the rental store - there is a shot where you can see the entrance of the store, and there is an electronic article surveillance detector on either side of the entrance to the store. This technology for use in a video rental store (for VHS tapes) did not exist in the 1980s.
Continuity mistake: When Alvin is making the big SOS sign, one shot shows the whole beach and Simon and Theodore are in the middle of the big letter O. In the next shot, they are at the O's edge.
Continuity mistake: After Popper gets the other penguins he opens the box and leaves it in the living room, but when the kid opens the door the box disappears.
Continuity mistake: When Johnny and Kate are having dinner in her apartment and Ambrose knocks on the door, Kate puts all the dinner away leaving a few candles on the table. The table is still like this when Kate and Ambrose leave the apartment, but when Johnny notices that the killer cleaner is in the apartment, the table is set up again.
Continuity mistake: In the scene where Linda and Blu are on the computer, when Tulio "communicates" with Blu, the computer is way too much to the right. It reappears when Blu starts squawking.
Other mistake: Grand-Santa has made 70 missions, and Santa (Malcolm) has just completed his 70th mission, totaling 140 years. Yet Grand-Santa is only 136 years old.
Suggested correction: Grandsanta's portrait is shown in the halls of the North Pole with the dates 1902-1941 (with Malcom having done 71 missions from 1941). Therefore he did 39 missions. That makes for a total of 109 years, meaning he was 27 when he took over from his own father.
Other mistake: When Greg is looking at the video of Rowley sitting on the foil ball, he notices it has only 4 views on YouTube. However, if you look closely, it has 24,963 comments - impossible if it's only been viewed 4 times.
Suggested correction: YouTube is broken. This kind of thing actually does happen in real life quite frequently. In fact, a video I was just watching had that problem.
Continuity mistake: Mitch's hair changes frequently when he is talking to his dad about the wedding.
Continuity mistake: When Jay slaps Si in the balls, his right hand is holding on to his bag, camera cuts and it's down by his side. Camera cuts again and it's back on his bag. (00:08:10)
Continuity mistake: When the bird first hits the RV, a blood stain is visible on the windshield. But on the exterior shot of the RV as it stops, the blood has disappeared. (00:26:50)
Continuity mistake: The false bottom of the locked desk drawer goes from being a solid piece when Elizabeth Halsey accesses it to a bottom that splits in half when the K9 officer accesses it.
Continuity mistake: When Rango was at the mayor's office, the mayor grabs out a jug of water, and he opens the lid. But in the next shot, the lid is sealed again.
Continuity mistake: When the guys take off to Bangkok on their direct flight, the plane is a 4 engine jet. When they land, it's a 2 engine jet.
Factual error: Passiflora Incarnata doesn't cause the symptoms described in the film. There was one remote incident where some of the symptoms (nausea) occurred but it can only happen if ingested which did not happen in this movie.
Continuity mistake: After Slide locks Josh's boss in the master bedroom closet within Mr. Fitzhugh's ex-apartment, he turns on the boombox at a high volume. Then later in the film, when they are retrieving the car through the window of the same apartment, the music is off. Then later, Josh's boss is seen trying to get out of the closet and the music is back on. (01:08:20 - 01:19:55)
Continuity mistake: At the end of the first film Mumble has lost most of his down, because his bow tie has yellow markings, however in the second movie he has somehow grown his down back.
Continuity mistake: When EB is young and is in the factory for the first time, he picks up some sweets off the factory line. The amount of sweets in his hand then changes between shots.
Continuity mistake: Just before the Smurfs are returned to the Winslows, Patrick consoles Grace. She is wearing black tights under her white dress. Then the Smurfs return on pigeon-back, and miraculously she is now bare-legged.
Continuity mistake: When Eddie walks in to the doctor's office and talks to "brows gone wild" the woman with the green shirt has it kind of loose around her breasts. The next shot of her, the green shirt is tight and tucked into her pants/skirt. Then on her way out the door, the green shirt is loose, the same way as the first shot.