Continuity mistake: In the scene where the Nemesis kills the 13 S.T.A.R.S members, after it blows up the sniper on the roof an additional S.T.A.R.S member can be seen outside the building on the right who wasn't there earlier. He then disappears shortly afterwards.
Continuity mistake: In the opening scene, Mort closes the door of his jeep before he goes into the hotel room. You can hear the sound of the door closing and it's visible in the rearview-mirror. As the camera moves out of the room, the jeep door is completely open. (00:02:05)
Suggested correction: The door just didn't actually catch. I've had cars like that, especially during the winter.
Given that we see it stay closed for almost 4 seconds and hear it catch, it's a valid mistake.
If you've ever lived where it snows a lot, you'd know that door catches accumulate moisture (ice) and can open slowly, as it did in this case.
Continuity mistake: When Dr. Gordon picks up his tape, the way he holds it changes instantly. (00:06:50)
Continuity mistake: When Vince leaves the freezer and is making his way onto the elevator, he is carrying a Baretta model pistol. When he shoots as the elevator doors are closing the camera cuts to a Glock model pistol, then back to the Baretta again. When the elevator reaches the upper level, the woman picks up the remains of the backfired pistol and it is back to the Glock. (01:21:15 - 01:24:30)
Continuity mistake: Towards the end of the movie, in the scene where Anna is taking the werewolf cure to Van Helsing and the vampire bride stops her on the large fallen pillar, she falls so she is in a sitting position with the cure in her left hand. She then switches it to her right. Then in the close-up shot, the cure is still in her left hand and she switches it again. (01:49:50)
Continuity mistake: In the scene where Lex is running in the abandoned whaler camp, the "shield" she is holding keeps changing hand between shots. (01:18:05)
Continuity mistake: As the priest descends down the rope ladder into the church for the first time he is handed a lantern by his friend. In the next shot the camera is looking down and you can see that the friend is holding the lantern. Then the next person goes down the same rope ladder and the friend is not holding the lantern, where did the lantern go?
Continuity mistake: When Ana hands over the file to Cora, Cora grabs the file on the side. When it cuts she grabs it on the top of the file. (00:01:20)
Continuity mistake: During the Sound Stage scene, Chucky and Tiffany kill the puppeteer by chopping his head off with wire. When the blood splatters all over Tiffany's and Chucky's faces, Tiffany's right eye is covered in blood. In the next shot there is no sign of blood in the eye at all.
Continuity mistake: When Blade has been rescued by Abigail and Hannibal and the 3 of them are approaching the hideout, notice in Abigail's back quiver there is one arrow left, yet in the next shot when they're walking up the stairs she has two.
Continuity mistake: When Gummer and Black Hand Kelly make an agreement, Kelly looks to his left and he isn't holding a glass. When it cuts, he is looking to his right and holding a glass. (00:40:35)
Continuity mistake: When Angelina Jolie destroys the mirror, you can see (just freeze the shot for an instant) that the mirror has been broken completely. Yet, in the next shot, she watches her reflection and there's still a lot of mirror unbroken. (01:31:30)
Continuity mistake: In the beginning, the cocaine dealer goes to a ghost town and is attacked by zombies. As he is running, his denim jacket goes from being partly pulled off, to completely off, to back on, to partly off, in about 5 shots. Very noticeable because he is wearing a white tank top.
Continuity mistake: When Jessie walks into the photography shop or studio to see if her photographs have sold she is wearing a tan jacket with a sheepskin collar and sheepskin lines on it. When she leaves the shop she is wearing a completely different jacket similar in color, but it has a hood.
Continuity mistake: After the scene where the first Umbrella Corp. employee gets eaten, the rest are discussing what just occurred. All their clothes appear to be dry. They just scrambled to get out of the river and should all be soaking wet.
Continuity mistake: When Ed drives Phil's Jaguar, its rearview mirror disappears and reappears repeatedly. (00:47:15 - 00:53:35)
Continuity mistake: When Karen goes into the cupboard upstairs, prior to meeting Toshio, she picks up a book. In one shot she picks it up by the page side, then when it cuts she is holding the spine side. (00:17:40)
Continuity mistake: When Wynn looks at Rains' file, the drawer her file is in is slightly open before he finds it. The shot cuts to Dodd reading the paper, then back to Wynn, and her drawer is shut. (00:32:40)
Continuity mistake: During the fight between the vampires and Anton, the vampire stabs Anton in the hand with the scissors and Anton kicks him in the face. When Anton starts his kicks the vampire is still holding the scissors that are imbedded in Anton but when the shot changes and Anton lands the kick, the vampire is a few steps to the side and not holding the scissors anymore. (00:27:55)
Continuity mistake: When the Professor is locked in the rec room, the door opens and while he's shooting there is a round handle to open and lock the door, mounted on the door. When he stops firing the gun, the shot cuts to him then back to the door and the round handle is gone. Later, when someone leaves the room it is back again.