Continuity mistake: When Alex is giving Izzy her medication, he is holding a water bottle and an unpeeled banana In his right hand. Then the banana magically disappears and he is holding only the water bottle. Immediately, the banana reappears and it is now peeled. This all takes place in three quick shot which are from different takes.
Continuity mistake: In the first overhead shot showing Izzy lying under the Christmas tree, you can see Meredith's hair to Izzy's left but then the the next shot is Meredith coming into the room and Izzy under the tree by herself. (00:41:05)Precidia Nicole Bordeaux
Continuity mistake: When Izzie is looking at the patient board, there are some lines on it which have been wiped out. But in the next scene we actually see Meredith walk to the board and wipe these exact same lines off (even though they were previously rubbed out...) (00:34:05)Hamster
Continuity mistake: When Alex comes in to talk to Meredith who is sitting on the floor, Meredith has two files and there is another file sitting up on the table next to her. By the end of the talk Meredith now has all three files although she never reached up for the one on the table. (00:16:15 - 00:17:55)Hamster