Continuity mistake: When Alex and George are trying to get out of the elevator that they are stuck in, watch the monitor screen attached to the gunshot victim. The lines on the monitor keep instantly changing appearance (from straight, to jagged, and then back, etc.), especially the middle blue line. (00:13:05)
Continuity mistake: When Meredith, Christina and Izzy are standing by the hospital hall balcony talking, the nurse, doctor and patient extras walking and passing in the background are inconsistent from shot to shot. In addition, the position of the three ladies arms / hands on the banister keeps changing during this scene. (00:12:35)
Continuity mistake: When Alex walks over to the desk that Derek is sitting behind, with the couple arguing in the background, there is a box of tissues with a tissue pulled so that it is almost out. In the next shot the tissue is barely out of the box. (00:26:20)
Continuity mistake: When Addison shows up at the end of the episode, the umbrella she holds keeps changing position and swapping hands between shots. (00:42:05)
Continuity mistake: Izzy tells the male patient she is a good doctor even though she was a model. Her hair is parted to the left and in the next shot it is parted to the right.
I Always Feel Like Somebody's Watchin' Me - S6-E3
Continuity mistake: When Alex is giving Izzy her medication, he is holding a water bottle and an unpeeled banana In his right hand. Then the banana magically disappears and he is holding only the water bottle. Immediately, the banana reappears and it is now peeled. This all takes place in three quick shot which are from different takes.
Continuity mistake: When Addison gives Derek the juju cocoa, he raises it to his lips three times in different shots, then is instantly holding it down by his waist in the next. (00:04:00)
Continuity mistake: When Izzie is looking at the patient board, there are some lines on it which have been wiped out. But in the next scene we actually see Meredith walk to the board and wipe these exact same lines off (even though they were previously rubbed out...) (00:34:05)
Band Aid Covers the Bullet Hole - S2-E21
Continuity mistake: When Callie places the hockey player's hand X-Ray on the chart, in the first shot it is on the left of the board. In the next it is dead centre and then back to being on the left again. (00:09:35)
(As We Know It) (Part II) - S2-E18
Continuity mistake: After Alex and Izzie have had sex in the closet, just before Izzie leaves in the first shot her hair is hanging in front of her shoulders. In the next shot as she walks out, it is all pulled back behind them. (00:13:35)
Continuity mistake: When Derek gives Meredith a white bag to hyperventilate into when she is crying in the closet, the large orange sticker on the side of the bag disappears and then reappears again. (00:35:30)
Continuity mistake: At the beginning when Derek is going to cook the trout and Addison is angry at him, the fridge door is shut. But in the next shot it is open a little bit and Derek closes it. (00:02:20)
Grandma Got Run Over By A Reindeer - S2-E12
Continuity mistake: Derek is talking to Addison while he takes his iPod, winds the earphones around it and puts it in his pocket. But then as he stands, the iPod is now clipped to his shirt and the earphones are hanging around his neck! (00:26:00)
Grandma Got Run Over By A Reindeer - S2-E12
Continuity mistake: At the beginning when Christina walks out and notices the small tree on the table, Burke lifts his red mug off of the counter to his mouth twice between two different shots. (00:01:30)
Thanks for the Memories - S2-E9
Continuity mistake: When Holden's son Colby comes out of his Dad's hospital room, the sliding door doesn't shut behind him and is slightly open. In the next shot it is suddenly fully shut. (00:26:55)
Thanks for the Memories - S2-E9
Continuity mistake: When Addison is talking to Derek on the boat, when she asks him about having his day off, her bag strap falls off, onto her arm. In the next shot it's up on her shoulder again. (00:01:35)
Thanks for the Memories - S2-E9
Continuity mistake: When Alex comes in to talk to Meredith who is sitting on the floor, Meredith has two files and there is another file sitting up on the table next to her. By the end of the talk Meredith now has all three files although she never reached up for the one on the table. (00:16:15 - 00:17:55)
Thanks for the Memories - S2-E9
Continuity mistake: When George's Dad runs his fingers down George's face and streaks lines of blood on his cheeks, in the following shots the appearance of the blood streaks changes. (00:25:00)
Thanks for the Memories - S2-E9
Continuity mistake: When Derek, Burke and Webber are talking in front of the board, the position of the bag strap on Derek's shoulder keeps changing. (00:03:10)
Thanks for the Memories - S2-E9
Continuity mistake: At the end when Derek is talking to Addison in the rain, a large wet strand of hair falls down onto his forehead. In the very next shot it is gone. (00:39:40)