Tracy Vetter: I dated him once.
Det. Nick Knight: Was it serious?
Tracy Vetter: No, I mean I dated him once.
Lucien LaCroix: Well I have seen stranger things in my time - men who walk through fire, children born speaking long-dead languages, and Harry Houdini had rather a nifty trick with handcuffs and a tank full of water.
Tracy: Now that I've expressly told you I don't need your help... I need your help.
Janette: That's not enthusiasm, it's desperation. They all dance as if Father Time were shooting bullets at their feet. Which, I suppose, he is.
Natalie: Nick, I'm in the habit of believing 10 unbelievable things before breakfast every day, starting with you.
Lucien LaCroix: If there is a god, must it be sane?
Janette: Poor Nicholas... tortured by a soul he hasn't got.
Lucien LaCroix: You don't look well, Don Constantine. Time's a bitch, isn't it?
Schanke: I'm curious what happens when we die, but I don't go on reconnaissance missions to find out.
Natalie: So, did you learn anything while you were dying on me?
Det. Nick Knight: Yeah, I learned that I have to live with the choice I made 800 years ago, and that forgiveness is not something you ask for, it's something that you earn here, among the living.
Answer: Nick was sick and tired of being an immortal bloodsucker. He wanted to be human, fall in love, get married, have children, grow old and die. As for Janette, according to her, she fell in love and the passion she felt "cured" her of her blood lust.