Continuity mistake: When Bill Murray first does his signature hand pray/bow maneuver for the praises from Tallahassee, Bill's hands go instantly from up in front of him to his pockets between camera angles.
Continuity mistake: The yellow Hummer goes from being initially dirty on the doors, to shiny clean when they get out to investigate the girls' Cadillac when it breaks down.
Continuity mistake: When Tallahassee and Columbus discover the abandoned Hummer, the camera pans in on the two hands attached to the steering wheel. From this angle, you can see Columbus looking in through the passenger door window while the door is shut. Immediately the camera pans to another angle, showing Tallahassee pulling one of the hands off the steering wheel and in this shot, Columbus's door is open. There wasn't enough time between shots for him to have opened the car door and there was no sound indicating that he had done so. (00:09:30)
Visible crew/equipment: The scene where Tallahassee is smashing the windows of a black parked van in anger, note a cameraman's legs come into shot below a poster in the shop window directly in front of the van.
Suggested correction: It's Tallahassee's legs! Extremely obvious in a window reflection.
Other mistake: After Columbus wakes up and realises the girl he let stay the night has turned into a zombie, he repeatedly hits her over the head with the commode top, but in the next shot, it is clean as a whistle - there is no blood or head matter on it at all. Also the bottom of the lid is real with grooves and crevices but after the second hit in the living room the bottom ridges are perfectly oval and smooth.
Suggested correction: He hit her in the place where there is hair on the head, he left no wound there, why in the world should be marks on the lid? It would be a mistake if there were marks after the impact shown.
Continuity mistake: When Little Rock takes Columbus and Tallahassee hostage inside the Hummer, she holds up a gun to Tallahassee's neck. In this shot, her hair is in front of her ear. The next time she is shown, where she shoots the gun through the sun roof, her hair is shown tucked behind her ear two different ways. Seconds later, when she takes Tallahassee's gun away from him, her hair is in front of her ear again. This pattern continues for the rest of the scene. Since both of her hands were on the gun, she shouldn't have been able to adjust her hair.
Continuity mistake: When Tallahassee first enters the fried Twinkie shop storeroom, there are Twinkies hanging out from the box. However when he goes to grab one he has to reach inside and there's not any outside the box anymore.
Continuity mistake: When Rule 4 (Seatbelts) is shown, the arms of the woman on the ground change position.
Factual error: During action sequences in the amusement park the girls attempt to escape in their Hummer, and a zombie head-butts the passenger window, causing it to shatter. As has been demonstrated on numerous occasions, including a Mythbusters program, tempered automotive glass will not break when struck by a blunt object and that would include a zombie's head. Only a blow from a sharply pointed object will break tempered glass.
Continuity mistake: When Tallahassee is taking cover in the booth, he is closing the security screens, but he does not lock them, He does not lock them later either, because you can see that the gate is slightly open, but later you can see a big lock holding the screen closed. (01:15:50 - 01:16:40)
Other mistake: When Columbus and Tallahassee open the back of the Hostess truck, a bunch of Snowballs fall out. During the shots from the inside the truck, on the right side, you can see some packages of Twinkies. It might not be easy to make out of the shape, but you can see the label on the package. I guess they should've done a more thorough search of the truck. (You might need widescreen to see this).
Continuity mistake: When the girls are on the blast off ride and they shoot the control box, you can see that they are 1/4 of the way down but in the next shot they are all the way at the top of the ride.
Continuity mistake: In the scene after Wichita and Little Rock stole Tallahassee's SUV, we see a huge shot of the camera panning downward as Columbus is talking to Tallahassee. We get to see a clear shot of the sky, which is very cloudy and no visible sun. As the camera moves with the two as they continue off screen, the next shot is from directly in front of them walking forward. However this time the sun is glaring brightly behind them leaving shadows from the buildings and lighting the road up with the bright sun. But in the shot before it was a very cloudy day. (00:27:20 - 00:28:20)