John: That's the second time you've tried to kill me today.
Jane: Oh, come on. It was just a little bomb.
The movie is supposed to take place in and around New York City, however during the car chase where Angelina and Brad are fighting off the three BMW's, a wide shot clearly shows a street sign announcing Los Angeles.
When John and Jane are questioning their former apparent target near the end of the film, look carefully at the guy's shirt - it's the logo from another Brad Pitt film, Fight Club.