Evolution

Plot hole: On the doors inside the white dome, and on the elevator door, it is marked "Vapor Lock." This is impossible due to the mine shaft opening. It can't be vapor locked when there's an opening.

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Plot hole: Because humans have a layer of subcutaneous fat under the skin, the bug that travels under Harry's skin would have caused not only significant damage but an amazing amount of pain while moving around. There would have also been severe internal damage caused by the bug if it traveled into his colon where they ended up removing it from.

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jerimiah

Plot hole: It is highly unlikely that government branches of the CDC and Military would be so lax on the security, protocols and enforcement of containment for what is perceived to be an alien life form to allow as many of the mishaps to occur throughout the film.

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jerimiah
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Mistakes

During the scene in the mall when the girl is in the dressing room, she keeps putting on more layers of clothing. But as they are shooting different shots she will have a hot pink shirt on, then it is back on the hanger, and then back on again. It switches back and forth many times.

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Trivia

In the scene where David And Orlando lead the class into the crater to see the meteor on the field trip if you pay attention to the background actors you can see a young John Cho. (Harold from Harold and Kumar).

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