Continuity mistake: When Lundgren bombs the prison bus, the aerial shots and the close-ups have nothing in common: In the aerial the bus is in a very narrow space next to a huge cliff, with nothing around but sand and rocks. In the first close-up the bus is rolling in a wide field, no sign of the cliff. In the second close-up a wooden fence and a house-shaped sign suddenly appear, only to disappear in the third close-up.
Plot hole: At the gas station exploding scene, we see van Damme and the reporter getting in the car and drive off. Just after van Damme and the reporter drive off, we see Lundren get up from the rear seats to try to strangle van Damme. Why would Lundren be there when firstly, they had no idea van Damme took the chip out of his leg, and secondly, after realising they had been set up, they had n idea where van Damme or the reporter would be at that stage. (00:51:54 - 00:52:30)
Other mistake: Scott started juicing himself up with strength enhancers after getting his memory back. Luc only had one (that he lifted from Scott's vest during the final fight), and not even a very thick syringe either. With that one syringe, his strength equalled Scott's. How is that only one small dosage was enough to match Scott's several doses worth of strength enhancement?
Other mistake: The Unisols are said to have been dropped into the water a mile and a half away from the dam. But, when they arrive, the three that you see are completely dry. Their hair isn't wet, and neither are their outfits. Scott has some on him, but that's most likely sweat because he's in the sun.