Revealing mistake: When Lucy is chained and locked up in the room by the Korean drug cartel, she is hit in the stomach by the Korean guy. Drugs start leaking into her stomach and her body, and she starts shaking and going up the wall and ceiling. When she is leaning against the wall and crawling up it, the way the gravity affects the chains and her hair shows that she is actually lying on the floor. (00:25:20)hamzehlou
Factual error: At the start of the film, cells are shown dividing. As each cell divides, the two new cells separate from each other and move apart from one another. In reality, cells do not move apart after dividing, but remain attached to one another.
Other mistake: In the hospital scene wherein Lucy disarms the gunmen and retrieves the briefcase of drugs, she plunges her hands inside a fallen man's abdomen to retrieve the last bag of drugs. Her hands are thus drenched in fresh, bright red blood. Lucy immediately steps to the corridor doors, places her bloody right hand against the door (plainly touching the glass) and pushes it open. But when she pauses and turns away, there are no bloody handprints, fingerprints or blood smears anywhere on the door.Charles Austin Miller
Deliberate mistake: When Lucy begins to travel through space and time during the climax, she's physically appearing in the difference places - both the native Americans and "Lucy" the ape react to her appropriately with shock. but when she appears in Paris, New York, etc. in crowded areas, nobody reacts to her at all, runs into her, etc. even though she's simply and seemingly magically appeared in the middle of bustling streets around dozens and dozens of people. (Especially strange in New York, when she's in the middle of a massive crowd.) Obviously done on purpose to make the scenes flow quicker, but an oddity nonetheless.TedStixon
Revealing mistake: After the drug addict gets shot, one of the henchmen lifts the dead drug addict's leg up and the other leg lifts up with it before the second henchman had a chance to grab it. It looks unrealistic as if it is a prop rather than a real human being dragged.
Continuity mistake: After her friend Richard coerces her to go into the hotel with the case to meet Mr. Jang, the man behind the counter who is talking to Mr. Jang asks her name. She says Richard is parking the car and he shows up at the window outside the hotel. Before he is shot, there is red 'blood' already on the window that was not entirely wiped off from previous takes.Dave Stanley