Continuity mistake: The bike that Tim uses to escape from Brian Cervier's ranch switches from a four stroke to a two stroke in the scene where it runs out of gas.
Continuity mistake: When Cillian Murphy's character is recording his message prior to entering the 'dead zone', our viewpoint is from within the monitor in front of him. As such, we see the on-screen image he sees, but reversed, floating between our vantage point and his image. At the bottom of the screen are touch-screen function 'buttons', again in reverse, which read (our left to right) 'RECORD', 'SEND', 'DELETE' and 'REVIEW'. But when our view changes to see the screen as we look over his shoulder from behind him, the visible buttons now read (right to left) 'SEND' and 'REVIEW' (he presses 'SEND'). They should be 'SEND' and 'RECORD'. (00:06:15)
Continuity mistake: When Nicole breaks the glowstick and splashes the liquid on the killer's mask, she starts to run. In the next shot of the killer, there is no liquid on the mask, yet it reappears in subsequent shots. (01:03:20)
Continuity mistake: In the end of the film where Willy and Ted stand together in Ted's house, Ted says to Willy "See, you can't touch me, ever". The shot goes to Willy and you can see his finger off the trigger, yet in the close-up on the trigger you can see that Willy's finger is inside the trigger-guard and he pulls it out. (01:46:15)
Continuity mistake: In the scene when Dawn is sitting on the edge of the tub after her shower, her "purity ring" switches from her left hand to her right and then back to her left hand in between close up and wide angle shots. (00:40:25)
Continuity mistake: When Andy gets sprayed with blood at the virus outbreak scene, when a sniper saves his life the blood splatter changes several times over the movie. (00:54:15)
Continuity mistake: When Stump is killed, we can see him falling off the cliff with the headband on his head. However, later on the movie, Amber finds his headband in the mine.
Suggested correction: The mutants could have taken his body through the mine.
Continuity mistake: Jason Statham is in a '70 Chevelle, following Jet Li. In some shots it's a '69 Chevelle, which has a noticeably different body style.
Continuity mistake: The train that Carol takes from Washington to Baltimore is an Amtrak Acela Express train, as can be seen in the station and interior shots. The exterior shot of the train passing by shows a different type of Amtrak train.
Continuity mistake: In the opening scene, the car's shadow changes with each shot from very long to very short.
Continuity mistake: Pickles is killed by multiple stab wounds to the chest and neck, as well as being scalped. But in the scene where Willa finds him, and when he is seen in his body bag, there is not a drop of blood to be seen anywhere on his face or clothes.
Continuity mistake: When Andy Konsong discovers his brother's mutilated body in the bloody swimming pool, he vomits, then tries calling for help on his cellphone. As he makes his call, the gigantic crocodile lunges out of the pool and bites off Andy's arm, cellphone and all, above the elbow. Andy screams, staggers and lands on his back, but his only injury thus far is his severed right arm. His mouth is not bloody at all, nor should it be. The camera cuts to another angle as the crocodile lunges a second time; but, before it even enters the frame and bites into his legs, Andy's mouth is suddenly full of blood, his teeth are bloody, and blood is streaming down his chin, even though he has suffered no abdominal injuries.
Continuity mistake: When the dead girl in a red raincoat appears in the doorway, at first the damage is on the right side of her face, next shot on the left, then in the third shot it has gone back to the right.
Continuity mistake: While McGahan is leaving the trailer with the widow (after giving his speech on heaven and hell) he closes the door. The next shot of him outside, the door is now wide open.
Continuity mistake: Standing in the subway talking about what the creatures were, the blood from the infected tract wound from the heroin needles is completely gone, as well as the entire wound itself. (00:46:30)
Continuity mistake: In the 2nd meeting between Emily and James, she brings him supplies. Emily is seen twisting at the cap on the bottled water before handing it to James. However, when she hands it to him, the cap is visibly still on the bottle. James is then seen removing the cap himself. He sets the cap on the table, takes a drink, then puts the bottle on the table. The next shot shows Emily with her hands in her lap then reaching for the bottle and putting the cap back on as if the cap was already in her hand. She never removed he cap. The cap would still be on the table where James put it. There is no way she could have retrieved that cap off the table without coming into camera view.
Continuity mistake: The two protagonists are having a conversation at a long table. Michael Caine sends a bottle of wine rolling across the table. Jude Law opens it and pours. The bottle label now faces him. After Caine says the line "I've never heard of an Italian called Tindale", Milo hasn't moved but the bottle faces the camera now. There's another subtle change in angle and level of the liquid a bit later when Caine says that his wife would get the "Tindelini" last name. (00:09:20)