Trivia: Original Dukes of Hazzard stars John Schneider, Tom Wopat and Catherine Bach were offered cameos in the movie. All three refused as they hated the screenplay.
Trivia: The Red Sox were originally scripted to lose the World Series. After the Sox actually did win the Series, the ending was changed.
Trivia: The painting of Jeremy that Todd Cleary ('Keir O'Donnell') creates and gives to Jeremy was kept by Vaughn after filming.
Trivia: When John and Jane are questioning their former apparent target near the end of the film, look carefully at the guy's shirt - it's the logo from another Brad Pitt film, Fight Club.
Trivia: At the very end of the film, when the group uses the Improbability Drive to go to the Restaurant at the End of the Universe, there are a lot of images that flash onto the screen when the drive is activated, so in the other parts of the film. In this case, the very last image shown is the face of Douglas Adams, the creator of the Hitchhiker series.
Trivia: During the opening pan shot of Dirk's stateroom, the article on the wall with the pic of the Titanic is a subtle reference to the Dirk Pitt adventure "Raise the Titanic", which was made into a movie in 1980, 6 years before the real Titanic was found.
Trivia: In the scene where Wallace fetches the giant rabbit after it has come off the van, Gromit turns on the radio, and we hear a song called "Bright Eyes" from the film 'Watership Down' a film about rabbits.
Trivia: There is a scene when the lemurs are showing a book called "To Serve Lemur". This is similar to one of the classic episodes of The Twilight Zone, "To Serve Man" when the "aliens" allegedly come in peace but actually want to eat the people of earth.
Trivia: Principal Powers says, "I'm not Wonder Woman, you know." She is played by Lynda Carter, the original Wonder Woman for the TV show.
Trivia: In the first scene in Max's office, there is a calendar showing the date as June 16. Leopold Bloom is a character in James Joyce's Ulysses, which recounts the events of a single day. June 16th.
Trivia: A popular film poster shows Emily and Victor reaching their hands toward one another. Emily's bony hand is on her right and Victor's suit and vest are backwards (note its buttons). Some say it was for legal reasons - Johnny Depp's name was supposed to appear on the poster first because of a contract, and they wanted the characters underneath the corresponding star names, hence the issue. Others say it was simply because the picture looked better with the bride on the right side.
Trivia: Not one cigarette is lit in this movie, or smoked.
Trivia: Australian comedian Mark Mitchell re-voiced Buck Cluck for the Australian release, but in an American accent.
Trivia: A little nod to another Blue Sky Studios Production, "Ice Age". When Rodney is looking around Robot city, he comes across a red robot that plays hip-hop. As Rodney walks away nervously ("Uh, n-n-never mind"), pause the frame just before the shot changes and you'll see (on the left) a yellow, mechanical Sid. Sid is the sloth (and the main character) from "Ice Age". (00:15:25)
Trivia: For Andy to get rid of the Teen Wolf look, actor Steve Carell's chest hair is really waxed by an actress, who is a non-professional waxer. Because there would only be one take of this disturbingly amusing scene, they set up five cameras - one on his 'friends', one over Andy, one on the waxer, one for wide shots, and one for close-ups of his chest. This scene was not scripted, so when the waxer laughs and Andy's friends are totally cracking up it was for real. Though it was strongly suggested to Steve to first trim his chest hair or to take a pain reliever before the taping, he refused, wanting to have the full cringe-effect caught on tape. In one close-up a bit of blood is actually seen bleeding up to the surface - it is not CGI. It took about seven weeks for his hair to grow back, much to chagrin of his wife, who wasn't crazy about his 'chest smiley'.
Trivia: The choice of Eva Mendes as the love interest was made because it was thought a white actress would alienate the black audience and a black actress would alienate the white audience, so they went for a Latino actress.