Continuity mistake: In the Eugene's Bike episode, when Arnold has to tie his shoe, he sets his books down on a bike in a bike rack. This causes the bike to tip over and makes all the other bikes in the rack to fall down. Eugene's bike falls into the middle of the street and get ran over. When Eugene finds out his bike is destroyed, he looks at Arnold and yells. Right after this you get a good look at the bike rack. You'll notice there are no bikes in or around the bike rack.
Continuity mistake: In "Miss Perfect", Helga, Rhonda, Sheena, Phoebe, and Nadine are cooking up ways to make Lila's (the new girl) life miserable. In one shot, Rhonda is wearing her new blue outfit. When the scene cuts to the boys and Lila, and then back to the five girls, Rhonda is wearing her standard red sweater and black pants. For the rest of that day, she is back in her new outfit.
Continuity mistake: In Sally's Comet when Gerald, Arnold, and Grandpa are in the traffic jam on the way to Hawk Mountain the position and type of cars around them change. When we first see the car there is a truck there and no room for them to turn around. When they do turn around then there is room and the truck is gone.