Doctor Who (1963)
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The Doctor: You can't rule the world in hiding. You've got to come out on the balcony sometimes and wave a tentacle, if you pardon the expression.
Trivia: Such was the popularity of Doctor Who in Britain in the mid-1960s that even the Beatles wanted to make an appearance in the show. So a scene was written into "The Chase" to allow them to appear. The idea had been devised of including a scene on the Time and Space Visualiser depicting a Beatles fiftieth-anniversary concert in 2015, with the Fab Four dressed up as old men. John, Paul, George, and Ringo themselves were interested in the proposition, but it was vetoed by their manager, Brian Epstein. It was then thought that an appearance by the Beatles on Top of the Pops might be used instead, but no such footage was available. Fortunately, the Beatles were scheduled to perform "Ticket to Ride" at Riverside Studios in Hammersmith on April 10th, 1965, and that footage was used instead.
Question: What caused the first Doctor to regenerate? Was it old age?
Chosen answer: No, it was the result of the Cybermen's draining Earth of energy to their world, that also affected the Doctor, draining his energy as well, causing him to regenerate.
Also In the episode it's said that his body was wearing thin.
Dan23