Continuity mistake: Malcolm's seat belt changes from on to off the first scene with him and his mom in the car. When it's a shot from the front it's on, but when it's a shot from the side (from the driver's/mom side) you can see that the part of the seat belt that's going across is now behind Malcolm, instead of on him like it was a second ago. This changes back and forth.
Continuity mistake: When the Tarantula is put on Hal at the zoo, the shot is only of a yellow shirt with the tarantula crawling on it. When the shot changes to where they show the whole Hal, you can easily tell that the tarantula is fake - it is larger than it was and is in a different spot on Hal's shirt.